The transforming growth factor-betas (TGF-βs) are synthesized as precursor proteins that
are modified intracellularly prior to secretion. One of the most relevant intracellular …

To achieve effective drug concentration at the intended site for a sufficient period of time is a
requisite desired for many drug formulations. For drugs intended to ocular delivery, its poor …

Pulmonary fibrosis is an irreversible accumulation of connective tissue in the interstitium of
the lung. The pathogenesis of pulmonary fibrosis is not well understood. Research on animal …

Despite the considerable progress in the classification of the idiopathic interstitial pneumonias
(IIPs), the lack of an international standard has resulted in variable and confusing …

An examination of quantum chemical and corrosion inhibition studies were made to see if
any clear links exist between the two. The results of quantum chemical calculations and …

Transforming growth factor-S (TGF-I3) can regulate cell growth and differentiation as well as
production of extracellular matrix proteins. Elevated production ofTGF-13 has been …

A rat model of bleomycin-induced pulmonary inflammation and fibrosis was used to
examine the relationship between collagen synthesis and transforming growth factor beta (TGF-beta…

… In a recent clinical trial, the conventional treatment regimen of a combination of prednisone,
azathioprine, and N-acetylcysteine was associated with an increased risk for death and …

Although it is recognized that three isoforms of transforming growth factor-beta (TGF-beta)
exist in mammals, their expression, distribution, and function in injury and repair are not well …

The congenital muscular dystrophies (CMD) are a heterogeneous group of autosomal
recessive disorders. A new pathomechanism has recently been identified in a group of these …