Biologic effects of leukocytes present in transfused cellular blood products
JO Bordin, NM Heddle, MA Blajchman - 1994 - ashpublications.org
… There is a smaller number in the various blood components, because some are lost during
their preparati~n.'~ Table 1 summarizes the approximate total number of leukocytes and …
their preparati~n.'~ Table 1 summarizes the approximate total number of leukocytes and …
A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpura
… Group 1 (n = 41) consisted of women who had severe thrombocytopenia (platelet count
lower than 50 × 10 9 /L) at any time during pregnancy or at time of delivery, and group 2 (n = 67) …
lower than 50 × 10 9 /L) at any time during pregnancy or at time of delivery, and group 2 (n = 67) …
Laboratory diagnosis of immune heparin-induced thrombocytopenia.
TE Warkentin, NM Heddle - Current Hematology Reports, 2003 - europepmc.org
Immune heparin-induced thrombocytopenia (HIT) is a distinct immunohematologic syndrome
in which laboratory detection of the pathogenic HIT antibodies is diagnostically useful. …
in which laboratory detection of the pathogenic HIT antibodies is diagnostically useful. …
Clinical practice guidelines from the AABB: red blood cell transfusion thresholds and storage
Importance More than 100 million units of blood are collected worldwide each year, yet the
indication for red blood cell (RBC) transfusion and the optimal length of RBC storage prior to …
indication for red blood cell (RBC) transfusion and the optimal length of RBC storage prior to …
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial
… Demographics of the baseline study population (n = 938) were balanced between groups
for all study populations (Table 1 and Supplementary Tables 2 and 3). The median age was …
for all study populations (Table 1 and Supplementary Tables 2 and 3). The median age was …
The Premature Infants in Need of Transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely …
…, RK Whyte, C Andersen, EV Asztalos, N Heddle… - The Journal of …, 2006 - Elsevier
… RESULTS: Four hundred fifty-one infants were randomly assigned to low (n = 223) or high
(n = 228) hemoglobin thresholds. Groups were similar, with mean birth weight of 770 g and …
(n = 228) hemoglobin thresholds. Groups were similar, with mean birth weight of 770 g and …
[HTML][HTML] The role of the plasma from platelet concentrates in transfusion reactions
NM Heddle, L Klama, J Singer… - New England journal …, 1994 - Mass Medical Soc
Background Febrile, nonhemolytic transfusion reactions are the most frequent adverse
reactions to platelets. A number of observations argue against the widely held view that these …
reactions to platelets. A number of observations argue against the widely held view that these …
A prospective study to identify the risk factors associated with acute reactions to platelet and red cell transfusions
NM Heddle, LN Klama, L Griffith, R Roberts… - …, 1993 - Wiley Online Library
It is generally assumed that febrile nonhemolytic transfusion reactions are an immunologically
mediated reaction involving the recipient's plasma and the white cells in the donor unit. …
mediated reaction involving the recipient's plasma and the white cells in the donor unit. …
Clinical outcomes following institution of the Canadian universal leukoreduction program for red blood cell transfusions
ContextA number of countries have implemented a policy of universal leukoreduction of their
blood supply, but the potential role of leukoreduction in decreasing postoperative mortality …
blood supply, but the potential role of leukoreduction in decreasing postoperative mortality …
Effect of short-term vs. long-term blood storage on mortality after transfusion
Background Randomized, controlled trials have suggested that the transfusion of blood
after prolonged storage does not increase the risk of adverse outcomes among patients, …
after prolonged storage does not increase the risk of adverse outcomes among patients, …