The implementation of real-time PCR for the diagnosis of malaria has been hampered by
poor sensitivity for the detection of mixed infections. We have optimized a method that …

… Correspondence should be addressed to Momar Ndao, momar.ndao@mcgill.ca … Copyright
© 2009 Momar Ndao. This is an open access article distributed under the Creative Commons …

The importation of malaria into a region where it is not endemic raises many concerns,
including the timely delivery of appropriate care, safety of the blood supply, and the risk of …

Cysteine proteases (CPs) play key roles in the pathogenesis of protozoan parasites, including
cell/tissue penetration, hydrolysis of host or parasite proteins, autophagy, and evasion or …

Methods for the diagnosis of parasitic infections have stagnated in the past three decades.
Labor-intensive methods such as microscopy still remain the mainstay of several diagnostic …

The cysteine protease cruzipain is essential for the viability, infectivity, and virulence of
Trypanosoma cruzi , the causative agent of Chagas disease. Thus, inhibitors of cruzipain are …

Background Schistosomiasis is a neglected tropical disease of global medical and veterinary
importance. As efforts to eliminate schistosomiasis as a public health problem and interrupt …

Background Fascioliasis is a worldwide parasitic disease of domestic animals caused by
helminths of the genus Fasciola. In many parts of the world, particularly in poor rural areas …

Cryptosporidiosis, caused by the protozoan parasite Cryptosporidium parvum , can stunt
infant growth and can be lethal in immunocompromised individuals. The most widely used …

Helminths contribute a larger global burden of disease than both malaria and tuberculosis.
These eukaryotes have caused human infections since before our earliest recorded history (ie…