Background— 3D transesophageal echocardiography (TEE) may provide more accurate
aortic annular and left ventricular outflow tract (LVOT) dimensions and geometries compared …

Regional left ventricular (LV) myocardial functional changes in early diabetic cardiomyopathy
have not been well documented. LV multidirectional strain and strain rate analyses by 2-…

Background— Fabry disease (FD) is an X-linked disorder of lysosomal metabolism affecting
multiple organs with cardiac disease being the leading cause of death. Current imaging …

Background— Quantification of mitral regurgitation severity with 2-dimensional (2D)
imaging techniques remains challenging. The present study compared the accuracy of 2D …

Importance Little is known about the association between bicuspid aortic valve (BAV)
morphologic findings and the degree of valvular dysfunction, presence of aortopathy, and …

Background— This large multicenter, international bicuspid aortic valve (BAV) registry aimed
to define the sex differences in prevalence, valve morphology, dysfunction (aortic stenosis/…

Objective We sought to evaluate the safety and efficacy of transcatheter aortic valve implantation
(TAVI) in patients with bicuspid aortic valve (BiAV). Background BiAV remains a relative …

… Author links open overlay panel Miriam Shanks MD a , Richard B. Thompson PhD b , Ian
D. Paterson MD a , Brendan Putko BSc a , Aneal Khan MSc, MD d , Alicia Chan MD c , Harald …

Anderson-Fabry disease (AFD) is a lysosomal storage disease caused by the inappropriate
accumulation of globotriaosylceramide in tissues due to a deficiency in the enzyme α-…

BACKGROUND: Advances in the minimally invasive mitral valve repair techniques increase
the demands on accurate and reliable morphologic assessment of the mitral valve using …