Molecular mechanisms underlying genotype‐dependent responses to dietary restriction
…, S Higgins, M Holmberg, KS Jeong, JR Kim… - Aging cell, 2013 - Wiley Online Library
Dietary restriction ( DR ) increases lifespan and attenuates age‐related phenotypes in many
organisms; however, the effect of DR on longevity of individuals in genetically …
organisms; however, the effect of DR on longevity of individuals in genetically …
Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms
Endothelial dysfunction contributes to cardiovascular diseases, including hypertension,
atherosclerosis, and coronary artery disease, which are also characterized by insulin resistance. …
atherosclerosis, and coronary artery disease, which are also characterized by insulin resistance. …
Explainable machine-learning predictions for the prevention of hypoxaemia during surgery
Although anaesthesiologists strive to avoid hypoxaemia during surgery, reliably predicting
future intraoperative hypoxaemia is not possible at present. Here, we report the development …
future intraoperative hypoxaemia is not possible at present. Here, we report the development …
A DNA barcode for land plants
…, PR Kesanakurti, JS Kim, YD Kim… - Proceedings of the …, 2009 - National Acad Sciences
DNA barcoding involves sequencing a standard region of DNA as a tool for species
identification. However, there has been no agreement on which region(s) should be used for …
identification. However, there has been no agreement on which region(s) should be used for …
[HTML][HTML] A 52-week placebo-controlled trial of evolocumab in hyperlipidemia
…, ML Monsalvo, K Tsirtsonis, JB Kim… - … England Journal of …, 2014 - Mass Medical Soc
Background Evolocumab, a monoclonal antibody that inhibits proprotein convertase
subtilisin/kexin type 9 (PCSK9), significantly reduced low-density lipoprotein (LDL) cholesterol …
subtilisin/kexin type 9 (PCSK9), significantly reduced low-density lipoprotein (LDL) cholesterol …
[HTML][HTML] New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate
Green tea is rich in polyphenol flavonoids including catechins. Epigallocatechin 3-gallate (EGCG)
is the most abundant and potent green tea catechin. EGCG has been extensively …
is the most abundant and potent green tea catechin. EGCG has been extensively …
Attenuation of the neural response to sad faces in major depressionby antidepressant treatment: a prospective, event-related functional magnetic resonance …
…, MJ Brammer, ND Walsh, J Kim… - Archives of general …, 2004 - jamanetwork.com
Background Depression is associated with interpersonal difficulties related to abnormalities
in affective facial processing. Objectives To map brain systems activated by sad facial affect …
in affective facial processing. Objectives To map brain systems activated by sad facial affect …
Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines
…, D Francis, NL Michael, JH Kim… - Science translational …, 2014 - science.org
The human phase 2B RV144 ALVAC-HIV vCP1521/AIDSVAX B/E vaccine trial, held in
Thailand, resulted in an estimated 31.2% efficacy against HIV infection. By contrast, vaccination …
Thailand, resulted in an estimated 31.2% efficacy against HIV infection. By contrast, vaccination …
[HTML][HTML] Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow
HSC homing, quiescence, and self-renewal depend on the bone marrow HSC niche. A large
proportion of solid tumor metastases are bone metastases, known to usurp HSC homing …
proportion of solid tumor metastases are bone metastases, known to usurp HSC homing …
[PDF][PDF] The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines
JI Kim, IC Ho, MJ Grusby, LH Glimcher - Immunity, 1999 - cell.com
IL-4 promotes the differentiation of naive CD4 + T cells into IL-4-producing T helper 2 (Th2)
cells. Previous work provided suggestive but not conclusive evidence that the transcription …
cells. Previous work provided suggestive but not conclusive evidence that the transcription …