Breast cancer stem cells (CSCs) can be identified by increased Aldefluor fluorescence
caused by increased expression of aldehyde dehydrogenase 1A3 (ALDH1A3), as well as …

INTRODUCTION: Incisional biopsies, including the diagnostic core needle biopsy (CNB),
routinely performed before surgical excision of breast cancer tumors are hypothesized to …

NAD + is a key metabolic redox cofactor that is regenerated from nicotinamide through the
NAD + salvage pathway. Here, we find that inhibiting the NAD + salvage pathway depletes …

Background. Extrapulmonary inflammatory pseudotumor (plasma cell granuloma) is an
uncommon lesion in adults and children, and little is known either of its etiology or clinical …

BACKGROUND:: There are many reports on the complications that occur at the time of insertion
and during the life of central venous indwelling catheters. However, there is no literature …

Immunogenic cell death (ICD) activates both innate and adaptive arms of the immune system
during apoptotic cancer cell death. With respect to cancer immunotherapy, the process of …

Introduction Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell (CSC) marker
and in breast cancer it is associated with triple-negative/basal-like subtypes and aggressive …

Reticulon-4 (RTN4), commonly known as a neurite outgrowth inhibitor (Nogo), is emerging
as an important player in human cancers. Clinically, we found lower RTN4 expression in …

This study proposes targeted metabolic reprogramming as a valid combinatorial strategy to
enhance the translational efficacy of oncolytic virus–based cancer therapies. …

Oncolytic reovirus preferentially targets and kills cancer cells via the process of oncolysis,
and additionally drives clinically favorable antitumor T cell responses that form protective …