Fast, definitive diagnosis of Creutzfeldt-Jakob disease (CJD) is important in assessing
patient care options and transmission risks. Real-time quaking-induced conversion (RT-QuIC) …

Cellular prion protein (PrP C ) is a glycophosphatidylinositol (GPI)–anchored protein, of
unknown function, found in a number of tissues throughout the body, including several blood …

Background Human prion diseases are rare and usually rapidly fatal neurodegenerative
disorders, the most common being sporadic Creutzfeldt-Jakob disease (sCJD). Variants in the …

Background To better characterize the value of cerebrospinal fluid (CSF) proteins as diagnostic
markers in a clinical population of subacute encephalopathy patients with relatively low …

Widely expressed in the adult central nervous system, the cellular prion protein (PrP C ) is
implicated in a variety of processes, including neuronal excitability. Dipeptidyl aminopeptidase…

The epidemiology and possibly the etiology of bovine spongiform encephalopathy (BSE)
have recently been recognized to be heterogeneous. In particular, three types [classical (C) …

Creutzfeldt-Jakob disease (CJD) comprises a group of transmissible neurodegenerative
diseases with vast phenotypic diversity. Sporadic CJD heterogeneity is predominantly …

THE PRION DISEASES POSE UNIQUE SCIENTIFIC, medical, veterinary and regulatory
challenges. Here, we summarize current information bearing on the natural history, …

To explore pathogenesis in a young Gerstmann-Sträussler-Scheinker Disease (GSS) patient,
the corresponding mutation, an eight-residue duplication in the hydrophobic region (HR), …

In this study, we compared antigenic (hemagglutination inhibition (HI) assay) and molecular
(sequencing of the hemagglutinin (HA1) gene) characterization of influenza isolates …