The incidence of acute myeloid leukaemia (AML) increases with age and mortality exceeds
90% when diagnosed after age 65. Most cases arise without any detectable early symptoms …

Background: The higher risk of death resulting from excess adiposity may be attenuated by
physical activity (PA). However, the theoretical number of deaths reduced by eliminating …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

OBJECTIVE: To extend the understanding of burnout in elite athletes, including personal
experiences and perceived antecedents. DESIGN AND METHODS: Semi-structured in-depth …

Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Background: Some, but not all, published results have shown an association between
circulating blood levels of some insulin-like growth factors (IGFs) and their binding proteins (…

We conducted imputation to the 1000 Genomes Project of four genome-wide association
studies of lung cancer in populations of European ancestry (11,348 cases and 15,861 controls) …

Purpose Human papillomavirus type 16 (HPV16) infection is causing an increasing number
of oropharyngeal cancers in the United States and Europe. The aim of our study was to …

Systemic inflammation markers have been linked to increased cancer risk and mortality in a
number of studies. However, few studies have estimated pre-diagnostic associations of …

We conducted a two-stage genome-wide association study of renal cell carcinoma (RCC) in
3,772 affected individuals (cases) and 8,505 controls of European background from 11 …