Background Reducing the actions of the renin-angiotensin-aldosterone system with
angiotensin-converting enzyme inhibitors (ACEIs) slows nephropathy progression in patients with or …

As end-stage renal disease (ESRD) has a four times higher incidence in African Americans
compared to European Americans, we hypothesized that susceptibility alleles for ESRD …

… 1 , Charles B Cangro, Sundaram Hariharan, Dondald E Hricik, Ronald H Kerman, David
Roth, David N Rush, Miguel A Vazquez, Matthew R Weir; American Society of Transplantation …

Background Hyperkalemia is a potential threat to patient safety in chronic kidney disease (CKD).
This study determined the incidence of hyperkalemia in CKD and whether it is …

Background The Avoiding Cardiovascular Events through Combination Therapy in Patients
Living with Systolic Hypertension (ACCOMPLISH) trial showed that initial antihypertensive …

Background Hyperkalemia increases the risk of death and limits the use of inhibitors of the
renin–angiotensin–aldosterone system (RAAS) in high-risk patients. We assessed the safety …

The challenges inherent in conducting accurate, clinically effective, and cost-effective
cardiac evaluations among transplantation candidates relate to the large size of the target …

Background Clinical trials of nephropathy in people with type 2 diabetes mellitus have not
examined the effects of systolic blood pressure (SBP) or pulse pressure (PP) on the time to end…

Angiotensin II plays a central role in the regulation of systemic arterial pressure through its
systemic synthesis via the renin-angiotensin-aldosterone cascade. It acts directly on vascular …

ABSTRACT. Polyoma virus (PV) can cause interstitial nephritis and lead to graft failure in renal
transplant recipients. The clinical course of patients with polyoma virus nephritis (PVN) is …