Self-collected saline gargle samples as an alternative to health care worker-collected nasopharyngeal swabs for COVID-19 diagnosis in outpatients
…, A Pabbi, S Hannam-Clark, M Charles… - Journal of clinical …, 2021 - Am Soc Microbiol
We assessed the performance, stability, and user acceptability of swab-independent self-collected
saliva and saline mouth rinse/gargle sample types for the molecular detection of …
saliva and saline mouth rinse/gargle sample types for the molecular detection of …
Evaluation of the BioFireŽ COVID-19 test and Respiratory Panel 2.1 for rapid identification of SARS-CoV-2 in nasopharyngeal swab samples
…, K Locher, M Caza, L Li, V Lavergne, M Charles - … and infectious disease, 2021 - Elsevier
The BioFireŽ COVID-19 Test and Respiratory Panel 2.1 (RP2.1) are rapid, fully automated
assays for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in …
assays for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in …
Legionella micdadei brain abscess
M Charles, E Johnson, A Macyk-Davey… - Journal of Clinical …, 2013 - Am Soc Microbiol
… Authors: Marthe Charles, Edward Johnson, Andrea Macyk-Davey, Monica Henry, Jan-Erik
Nilsson, Lil Miedzinski, George Zahariadis… Marthe Charles … Address correspondence to …
Nilsson, Lil Miedzinski, George Zahariadis… Marthe Charles … Address correspondence to …
[HTML][HTML] Nanopore metagenomic sequencing for detection and characterization of SARS-CoV-2 in clinical samples
…, C Nelson, MB Bonsall, K Locher, M Charles… - PLoS …, 2021 - journals.plos.org
Objectives The COVID-19 pandemic has underscored the need for rapid novel diagnostic
strategies. Metagenomic Next-Generation Sequencing (mNGS) may allow for the detection of …
strategies. Metagenomic Next-Generation Sequencing (mNGS) may allow for the detection of …
[HTML][HTML] Alterations in the nasopharyngeal microbiome associated with SARS-CoV-2 infection status and disease severity
…, K Locher, C MacDonald, SD Chorlton, M Charles… - PLoS …, 2022 - journals.plos.org
Objectives The COVID-19 pandemic and ensuing public health emergency has emphasized
the need to study SARS-CoV-2 pathogenesis. The human microbiome has been shown to …
the need to study SARS-CoV-2 pathogenesis. The human microbiome has been shown to …
[HTML][HTML] BugSplit enables genome-resolved metagenomics through highly accurate taxonomic binning of metagenomic assemblies
…, C Nelson, MB Bonsall, K Locher, M Charles… - Communications …, 2022 - nature.com
A large gap remains between sequencing a microbial community and characterizing all of the
organisms inside of it. Here we develop a novel method to taxonomically bin metagenomic …
organisms inside of it. Here we develop a novel method to taxonomically bin metagenomic …
[HTML][HTML] SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British Columbia
…, D Cook, B Bates, L Burns, S Masud, M Charles… - Journal of Clinical …, 2021 - Elsevier
Background SARS-CoV-2 antibody testing is required for estimating population seroprevalence
and vaccine response studies. It may also increase case identification when used as an …
and vaccine response studies. It may also increase case identification when used as an …
First reported outbreak of the emerging pathogen Candida auris in Canada
…, L Hoang, M Dawar, M Charles - American Journal of …, 2021 - Elsevier
Background Candida auris was first described in Japan in 2009 and has since been detected
in over 40 countries. The yeast is concerning for multiple reasons, primarily: (1) challenges …
in over 40 countries. The yeast is concerning for multiple reasons, primarily: (1) challenges …
An engineered nanocomposite copper coating with enhanced antibacterial efficacy
…, B Velapatino, EA Bryce, MK Charles… - Advanced Materials …, 2022 - Wiley Online Library
Contaminated surfaces are a major source of nosocomial infection. To reduce microbial
bioburden and surface‐based transmission of infectious disease, the use of antibacterial and self…
bioburden and surface‐based transmission of infectious disease, the use of antibacterial and self…
[HTML][HTML] A nested cohort 5-year Canadian surveillance of Gram-negative antimicrobial resistance for optimized antimicrobial therapy
J Blondeau, MK Charles, V Loo, H Adam… - Scientific Reports, 2023 - nature.com
We analyzed 5 years (2016–2020) of nested Canadian data from the Study for Monitoring
Antimicrobial Resistance Trends (SMART) to identify pathogen predominance and …
Antimicrobial Resistance Trends (SMART) to identify pathogen predominance and …