A functional serotonin transporter promoter polymorphism, HTTLPR, alters the risk of disease
as well as brain morphometry and function. Here, we show that HTTLPR is functionally …

Although obsessive-compulsive disorder (OCD) has long been a unitary diagnosis, there is
much recent interest in its potential heterogeneity, as manifested by symptom subgroups. …

Context There is strong evidence from family and twin studies that genetic determinants
play an important role in the etiology of obsessive-compulsive disorder (OCD). In the only …

Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative (…

The direct estimation of heritability from genome-wide common variant data as implemented
in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to …

Rationale Recent investigation suggests that a reversible glutamatergically mediated
thalamocortical-striatal dysfunction may serve as a reliable pathophysiological and treatment …

Epidemiologic and neurobiologic evidence suggests that patients with comorbid obsessive–compulsive
disorder (OCD) and schizophrenia may represent a special category among …

Objective: An anxiety disorder severely affects the sufferer's quality of life (QOL), and this
may be particularly true of those with obsessive–compulsive disorder (OCD). This study …

The present study investigated episodic memory functioning in: (1) obsessive compulsive
disorder (OCD) patients with primarily checking symptoms (ie checkers); (2) OCD patients …

Importance For a small percentage of obsessive-compulsive disorder (OCD) cases exhibiting
additional neuropsychiatric symptoms, it was proposed that neuroinflammation occurs in …