The prognosis of decompensated cirrhosis resulting from chronic hepatitis B is poor, and the
benefits of treatment with interferon are outweighed by serious side effects and by the risk of …

The disease burden of hepatitis C virus ( HCV ) is expected to increase as the infected population
ages. A modelling approach was used to estimate the total number of viremic infections…

In this study, activation of the mitogen-activated protein kinase kinase (MEK)/extracellular
signal-regulated kinase (ERK) signalling pathway was analyzed in proliferating rat …

Background/Aim: Quantitative measurement of hepatic iron by biochemical analysis of liver
biopsy samples is required to assess hepatic iron stores accurately. Cirrhotic livers, however, …

BACKGROUND: Chronic infection with hepatitis C virus (HCV) is a major cause of cirrhosis,
hepatocellular carcinoma and liver transplantation.OBJECTIVE: To estimate the burden of …

The clinical use of doxorubicin (DOX), an anthracycline chemotherapeutic agent, is limited
by cardiotoxicity. The possible involvement of iron in DOX-induced cardiotoxicity became …

Several hepatocyte mitogens have been identified, but the signals triggering the G 0 /G 1
transition and cell cycle progression of hepatocytes remain unknown. Using hepatocyte …

The treatment of hepatitis C has become safer, better tolerated and more effective owing to
the availability of direct-acting antivirals for nearly all patients; this guideline advocates …

Importance The COVID-19 pandemic is the greatest global test of health leadership of our
generation. There is an urgent need to provide guidance for leaders at all levels during the …

Inflammatory immune cells can modulate activation of hepatic stellate cells (HSCs) and
progression of liver fibrosis. Type 3 inflammation characterized by production of interleukin-17A (…