Background Enteral nutrition (EN) is recommended as the preferred route for early nutrition
therapy in critically ill adults over parenteral nutrition (PN). A recent large randomized …

Adipose tissue has an important endocrine function in the regulation of whole-body metabolism.
Obesity leads to a chronic low-grade inflammation of the adipose tissue, which disrupts …

Clinical practice guidelines (CPGs) are systematically developed statements to assist practitioners
and patient decisions about appropriate healthcare for specific clinical circumstances, …

MYC contributes to the pathogenesis of a majority of human cancers, yet strategies to
modulate the function of the c-Myc oncoprotein do not exist. Toward this objective, we have …

The NAD-dependent deacetylase SIR2 and the forkhead transcription factor DAF-16
regulate lifespan in model organisms, such as yeast and C. elegans. Here we show that the …

The major facilitator superfamily represents the largest group of secondary membrane
transporters in the cell. Here we report the 3.3 angstrom resolution structure of a member of this …

… The solution was neutralized with 1 M KHCO 3 , centrifuged briefly, and the supernatant …
We thank Brian Lavan and Francine M. Gregoire for helpful advice on glucose tolerance tests. …

… Th’ng, and M. Lemieux, unpublished data) was immunopurified by adsorption and elution
from recombinant His-tagged SIR2α protein made in bacteria. After incubation with the primary …

The main protease, M pro (or 3CL pro ) in SARS-CoV-2 is a viable drug target because of its
essential role in the cleavage of the virus polypeptide. Feline infectious peritonitis, a fatal …

To find use in electronics, single-walled carbon nanotubes need to be efficiently separated
by electronic type and aligned to ensure optimal and reproducible electronic properties. We …