User profiles for M. G. Blennerhassett

Michael Blennerhassett

Queen's University
Verified email at queensu.ca
Cited by 4296

Control of myometrial contractility: role and regulation of gap junctions.

RE Garfield, MG Blennerhassett… - Oxford reviews of …, 1988 - europepmc.org
In this review we have attempted to describe the morphology and electrophysiology of the
myometrium and also the myogenic, neurogenic and hormonal systems which control its …

Damage to the enteric nervous system in experimental colitis

S Sanovic, DP Lamb, MG Blennerhassett - The American journal of …, 1999 - Elsevier
… For this, 29 mg of DNBS was dissolved in 250 μl of 50% ethanol and instilled into the colon
8 cm proximal to the anus with a PE50 catheter while the rat was under light anesthesia. …

Neuroimmune mechanisms in health and disease: 2. Disease.

…, CN Bernstein, MG Blennerhassett… - CMAJ: Canadian …, 1996 - ncbi.nlm.nih.gov
In the second part of their article on the emerging field of neuroimmunology, the authors
present an overview of the role of neuroimmune mechanisms in defence against infectious …

Glial cell line‐derived neurotrophic factor is a key neurotrophin in the postnatal enteric nervous system

…, AY Li, DG Nair, MG Blennerhassett - …, 2011 - Wiley Online Library
Background The enteric nervous system (ENS) continues its structural and functional growth
after birth, with formation of ganglia and the innervation of growing smooth muscle. However…

Picomolar doses of substance P trigger electrical responses in mast cells without degranulation

…, J Bienenstock, MG Blennerhassett - American Journal of …, 1994 - journals.physiology.org
The nervous and immune systems may communicate through the action of neurotransmitters
on mast cells. We used patchclamp electrophysiology to assess the responses of rat …

Inflammation causes hyperplasia and hypertrophy in smooth muscle of rat small intestine

MG Blennerhassett, P Vignjevic… - American Journal …, 1992 - journals.physiology.org
Inflammation of the rat jejunum with Trichinella spiralis causes altered smooth muscle
contractility by day 6 postinfection (PI). We investigated the association of structural change in the …

The pro-inflammatory cytokines IL-1β and TNFα are neurotrophic for enteric neurons

…, MJ Ropeleski, MG Blennerhassett - Journal of …, 2013 - Soc Neuroscience
Intestinal inflammation causes initial axonal degeneration and neuronal death but subsequent
axon outgrowth from surviving neurons restores innervation density to the target smooth …

The selective beneficial effects of nitric oxide inhibition in experimental colitis

…, SM Collins, MG Blennerhassett - American Journal …, 1995 - journals.physiology.org
We investigated the involvement of nitric oxide in trinitrobenzene-sulfonic acid (TNB) colitis.
Every 24 h after TNB, rats were orally dosed with NG-nitro-L-arginine methyl ester (L-NAME; …

Nerve growth factor modifies the expression of inflammatory cytokines by mast cells via a prostanoid-dependent mechanism

JS Marshall, K Gomi, MG Blennerhassett… - The Journal of …, 1999 - journals.aai.org
Nerve growth factor (NGF) is well recognized to have a number of potent effects on mast
cells, including increasing mast cell numbers in vivo and inducing mast cell degranulation in …

Intercellular communication in smooth muscle

JD Huizinga, LWC Liu, MG Blennerhassett… - Experientia, 1992 - Springer
The functioning of a group of cells as a tissue depends on intercellular communication; an
example is the spread of action potentials through intestinal tissue resulting in synchronized …