[HTML][HTML] rAAV-compatible MiniPromoters for restricted expression in the brain and eye
…, SL Lam, TC Lengyell, RJ Bonaguro, LJ Borretta… - Molecular brain, 2016 - Springer
Background Small promoters that recapitulate endogenous gene expression patterns are
important for basic, preclinical, and now clinical research. Recently, there has been a …
important for basic, preclinical, and now clinical research. Recently, there has been a …
[HTML][HTML] Targeted CNS delivery using human MiniPromoters and demonstrated compatibility with adeno-associated viral vectors
…, S Laprise, M Zhou, AY Chou, L Borretta… - … Therapy-Methods & …, 2014 - cell.com
Critical for human gene therapy is the availability of small promoters tools to drive gene
expression in a highly specific and reproducible manner. We tackled this challenge by …
expression in a highly specific and reproducible manner. We tackled this challenge by …
Lymphomatoid Papulosis With T-cell Receptor–Gamma Delta Expression: A Clinicopathologic Case-series of 26 Patients of an Underrecognized Immunophenotypic …
…, S Pileri, A Pileri, V Tabanelli, L Borretta… - The American Journal …, 2024 - journals.lww.com
Lymphomatoid papulosis (LyP) has several histopathologic presentations. LyP featuring
gamma-delta (γδ) T-cell receptor expression may masquerade as and may be misdiagnosed as …
gamma-delta (γδ) T-cell receptor expression may masquerade as and may be misdiagnosed as …
Peripherally inserted central catheters in pediatric oncology patients: a 15-year population-based review from Maritimes, Canada
L Borretta, T MacDonald, C Digout… - Journal of pediatric …, 2018 - journals.lww.com
The present population-based study evaluates the management and complications of
peripherally inserted central catheters (PICC) in all pediatric oncology patients diagnosed in …
peripherally inserted central catheters (PICC) in all pediatric oncology patients diagnosed in …
[HTML][HTML] TERT promoter mutations in atypical melanocytic lesions: A series of seven cases with adverse melanoma-specific outcome
R Huber, J Lee, L Borretta, B Tessier-Cloutier, A Lum… - Human Pathology, 2024 - Elsevier
The majority of melanocytic proliferations can be readily categorized as benign or malignant
based on histologic assessment under the microscope by a trained dermatopathologist. …
based on histologic assessment under the microscope by a trained dermatopathologist. …
An atypical presentation of lupus vulgaris
L Borretta, P Green - CMAJ, 2017 - Can Med Assoc
A 25-year-old man was referred to the dermatology clinic with a nonhealing ulcer on the front
of his right leg, following a localized minor trauma six months earlier. The patient was born …
of his right leg, following a localized minor trauma six months earlier. The patient was born …
A case of Whipple Disease with cutaneous manifestations
L Borretta, NM Walsh, V Bakowsky… - The American Journal …, 2021 - journals.lww.com
Whipple disease (WD) is a rare bacterial infectious disease that is classically characterized
by years of arthralgia, followed by malabsorption, diarrhea, and weight loss. However, WD …
by years of arthralgia, followed by malabsorption, diarrhea, and weight loss. However, WD …
[HTML][HTML] Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice
…, KG Banks, RJ Bonaguro, SC McInerny, L Borretta… - BMC biology, 2013 - Springer
Background The next big challenge in human genetics is understanding the 98% of the
genome that comprises non-coding DNA. Hidden in this DNA are sequences critical for gene …
genome that comprises non-coding DNA. Hidden in this DNA are sequences critical for gene …
CD34 staining in disorders of collagen degeneration other than morphea
LJ Borretta, RI Crawford - The American Journal of …, 2020 - journals.lww.com
CD34 Staining in Disorders of Collagen Degeneration Other Th... : The American Journal of
Dermatopathology CD34 Staining in Disorders of Collagen Degeneration Other Than …
Dermatopathology CD34 Staining in Disorders of Collagen Degeneration Other Than …
CD34 staining as a useful tool in disorders of collagen degeneration
JMC Lee, LJ Borretta, RI Crawford - The American Journal of …, 2022 - journals.lww.com
The human progenitor-cell antigen CD34 is expressed in dermal dendritic cells and is lost
in several disorders affecting dermal collagen. The loss of CD34 immunohistochemical …
in several disorders affecting dermal collagen. The loss of CD34 immunohistochemical …