… Linda E Lévesque, assistant professor of epidemiology1… Correspondence to: L
Lévesque linda.levesque{at}queensu.ca … Articles by Linda E Lévesque …

ContextThiazolidinediones (TZDs), used to treat type 2 diabetes, are associated with an
excess risk of congestive heart failure and possibly acute myocardial infarction. However, the …

Objectives To describe the use and reporting of interrupted time series methods in drug
utilization research. Study Design and Setting We completed a systematic search of MEDLINE, …

Conventional nonsteroidal antiinflammatory drugs (NSAIDs) are associated with acute renal
failure, but cyclooxygenase-2 inhibitors have not been comparatively evaluated. The …

Background: Cyclooxygenase-2 (COX-2) selective inhibitors have been marketed since 1999
as safer alternatives to nonsteroidal anti-inflammatory drugs (NSAIDs). Debate about their …

Background: Suboptimal human papillomavirus (HPV) vaccine coverage in some jurisdictions
is partly attributed to fears that vaccination may increase risky sexual behaviour. We …

Objectives : The purpose of this study was to determine if statins (hydroxymethylglutaryl
CoA reductase inhibitors [HMG-CoA]), angiotensin-converting enzyme (ACE) inhibitors, and …

BACKGROUND: Despite widespread promotion of quadrivalent human papillomavirus (qHPV)
vaccination for young girls, there is limited information on the vaccine’s real-world …

Background: Isotretinoin, a teratogen, is widely used to treat cystic acne. Although the risks of
pregnancy during isotretinoin therapy are well recognized, there are doubts about the level …

The benefit of oral bisphosphonates in reducing fracture risk in glucocorticoid‐induced
osteoporosis is controversial. We aimed to estimate the effectiveness of oral bisphosphonates in …