[PDF][PDF] Adjunct immunotherapies for the management of severely ill COVID-19 patients
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). It has infected millions, with more than 275,000 fatal cases as of …
coronavirus 2 (SARS-CoV-2). It has infected millions, with more than 275,000 fatal cases as of …
[HTML][HTML] Intravenous immunoglobulin as clinical immune-modulating therapy
In chronic inflammatory demyelinating polyneuropathy, evidence for the use of immunoglobulin
(2 g/kg) is supported by a meta-analysis of seven RCTs involving 287 patients. 11 …
(2 g/kg) is supported by a meta-analysis of seven RCTs involving 287 patients. 11 …
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
…, C Prando, A Bondarenko, AN Spaan, L Gilardin… - Science …, 2021 - science.org
Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/ml; in plasma
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
…, A Bondarenko, AN Spaan, L Gilardin… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR)
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …
High risk of cancer in autoimmune necrotizing myopathies: usefulness of myositis specific antibody
…, B Hervier, Y Schoindre, A Rigolet, L Gilardin… - Brain, 2016 - academic.oup.com
Cancer can occur in patients with inflammatory myopathies. This association is mainly
observed in dermatomyositis, and myositis-specific antibodies have allowed us to delineate …
observed in dermatomyositis, and myositis-specific antibodies have allowed us to delineate …
Kinetic profiles and management of hepatitis B virus reactivation in patients with immune‐mediated inflammatory diseases
N Droz, L Gilardin, P Cacoub… - Arthritis care & …, 2013 - Wiley Online Library
Objective Immunosuppressive therapy may trigger hepatitis B virus (HBV) reactivation for
increased morbidity and mortality. We aimed to describe HBV reactivation in patients receiving …
increased morbidity and mortality. We aimed to describe HBV reactivation in patients receiving …
[HTML][HTML] Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy
Autophagy plays an important role in the regulation of autoimmune and autoinflammatory
responses of the immune cells. Defective autophagy process is associated with various …
responses of the immune cells. Defective autophagy process is associated with various …
Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE
Background Therapeutic normal IgG or intravenous immunoglobulin (IVIG) exerts anti-inflammatory
effects through several mutually nonexclusive mechanisms. Recent data in mouse …
effects through several mutually nonexclusive mechanisms. Recent data in mouse …
Anti-ADAMTS13 autoantibodies against cryptic epitopes in immune-mediated thrombotic thrombocytopenic purpura
…, J Voorberg, MA Azerad, L Gilardin… - Thrombosis and …, 2018 - thieme-connect.com
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by severe
ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member …
ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member …
Symptomatic muscular sarcoidosis: lessons from a nationwide multicenter study
…, J Haroche, A Mathian, M Pha, L Gilardin… - Neurology …, 2018 - AAN Enterprises
Objectives To describe clinicopathologic features of muscular sarcoidosis and the associated
sarcoidosis phenotype through a nationwide multicenter study. Methods Patients were …
sarcoidosis phenotype through a nationwide multicenter study. Methods Patients were …
