Ulcerative colitis (UC) is a common gastrointestinal disorder in adults. Recent advances in
pathophysiology, immunology, and pharmaceutical science have resulted in a large number …

Purpose: To assess the effectiveness of azathioprine and 6-mercaptopurine in inducing
remission of active Crohn disease and the effectiveness of azathioprine in maintaining remission …

Advances in immunology, biotechnology, and phar-maceutical science have resulted in an
unprecedented number of medications with potential application to the treatment of Crohn’s …

Crohn's disease is a heterogeneous entity. Previous attempts of classification have been
based primarily on anatomic location and behavior of disease. However, no uniform definition …

The efficacy and safety of 4-g 5-aminosalicylic acid enemas were assessed in 153 patients
with ulcerative colitis involving up to 50 cm of distal colon. Seventy-six patients received …

Background Corticosteroids are the most efficacious drugs for inducing remission in active
Crohn's disease, but their benefits are frequently offset by serious side effects. Budesonide is …

… Griffiths, Sutherland, and Ohlsson using the criteria outlined by Chalmers et a1.14 (see …
Sutherland, and Ohlsson have training in clinical epidemiology and biostatistics; Drs. Sutherland …

We conducted a prospective, observational cohort study designed to compare intestinal
permeability (IP) and development of multiple organ dysfunction syndrome (MODS) in a subset …

Oral 5‐aminosalicylic acid for maintenance of remission in ulcerative colitis - Sutherland, LR …
In an earlier meta‐analysis (Sutherland 1993), we found that the newer drugs were no more …

Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal
amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile …