Objectives : We sought to conduct a systematic review and meta-analysis of the cardiovascular
risk associated with the metabolic syndrome as defined by the 2001 National Cholesterol …

A recently documented correlate of anthropogenic climate change involves reductions in
body size, the nature and scale of the pattern leading to suggestions of a third universal …

… L Joseph has nothing to disclose. AE Lang received consultancy, Novartis, Teva, Abbott,
Allon Therapeutics, Avanir Pharmaceuticals, Merck, Medtronic, AbbVie, Biogen Idec, …

Background Among patients with non–small-cell lung cancer (NSCLC), data on intratumor
heterogeneity and cancer genome evolution have been limited to small retrospective cohorts. …

The early detection of relapse following primary surgery for non-small-cell lung cancer and
the characterization of emerging subclones, which seed metastatic sites, might offer new …

Objective To examine mortality rates in the largest systemic lupus erythematosus (SLE) cohort
ever assembled. Methods Our sample was a multisite international SLE cohort (23 centers…

Immune evasion is a hallmark of cancer. Losing the ability to present neoantigens through
human leukocyte antigen (HLA) loss may facilitate immune evasion. However, the …

Obesity has been associated with elevated levels of C ‐reactive protein ( CRP ), a marker of
inflammation and predictor of cardiovascular risk. The objective of this systematic review …

… Lawrence Joseph and Theresa Gyorkos are both research scholars, supported by the Fonds
de la Recherche en Sant6 du Quebec and the National Health Research and Development …

The integration of phylogenetics, phylogeography and palaeoenvironmental studies is
providing major insights into the historical forces that have shaped the Earth’s biomes. Yet our …