Expression and localization of matrix‐degrading metalloproteinases during colorectal tumorigenesis

KJ Newell, JP Witty, WH Rodgers… - Molecular …, 1994 - Wiley Online Library
The metalloproteinase matrilysin is widely expressed in the epithelial tumor cells of malignant
colorectal adenocarcinomas. Approximately 50% of benign adenomas also express low …

Venous invasion in colorectal cancer: impact of an elastin stain on detection and interobserver agreement among gastrointestinal and nongastrointestinal pathologists

…, DX Divaris, R Pandit, KJ Newell, J Liu… - The American journal …, 2013 - journals.lww.com
Venous invasion (VI) is an independent prognostic indicator in colorectal cancer and may
prompt consideration for adjuvant chemotherapy in patients with stage II tumors. Recent …

Modulation of Matrilysin Levels in Colon Carcinoma Cell Lines Affects Tumorigenicity in Vivo

JP Witty, S McDonnell, KJ Newell, P Cannon, M Navre… - Cancer Research, 1994 - AACR
The expression of the metalloproteinase matrilysin in the human colon carcinoma cell lines
SW480 and SW620 correlates with the ability of the SW620 cells to invade an artificial …

Reduction of intracellular pH as a possible mechanism for killing cells in acidic regions of solid tumors: effects of carbonylcyanide-3-chlorophenylhydrazone

KJ Newell, IF Tannock - Cancer research, 1989 - AACR
The environment of cells within solid tumors is known to be acidic relative to that in normal
tissue, and the viability of tumor cells may depend on mechanisms which maintain …

GEWF solution: an inexpensive, simple, and effective aid for the retrieval of lymph nodes from colorectal cancer resections

KJ Newell, BW Sawka, BF Rudrick… - … of pathology & …, 2001 - meridian.allenpress.com
Background.—Lymph node status is an important prognostic factor in the staging of colorectal
carcinoma. Several adjunctive solutions have been used to increase the yield of pericolic …

Matrilysin (matrix metalloproteinase‐7) expression in ulcerative colitis–related tumorigenesis

KJ Newell, LM Matrisian… - … : Published in cooperation …, 2002 - Wiley Online Library
Matrilysin (matrix metalloproteinase‐7) plays a part in the initiation and growth of colorectal
tumors; expression of this protein has been implicated in tumor invasion and metastasis. To …

Plastic bread-bag clips in the gastrointestinal tract: report of 5 cases and review of the literature

KJ Newell, B Taylor, JC Walton, EJ Tweedie - Cmaj, 2000 - Can Med Assoc
Plastic bread-bac clips have been identified as a cause of local perforation or obstruction at
many sites in the gastrointestinal tract. This study is the largest case series yet reported, …

The impact of knowledge transfer on the detection of venous invasion in colorectal cancer

…, A Pollett, CJ Streutker, DX Divaris, KJ Newell… - Human pathology, 2017 - Elsevier
Venous invasion (VI) is an independent predictor of hematogenous metastasis and mortality
in colorectal cancer (CRC) yet remains widely underreported. Its detection may require …

Feasibility and performance of elastin trichrome as a primary stain in colorectal cancer resection specimens: Results of an Interobserver variability study

…, A Deliallisi, KJ Newell, A Grin, J Conner… - The American Journal …, 2021 - journals.lww.com
Venous invasion (VI) is a powerful prognostic factor in colorectal cancer (CRC) that is widely
underreported. The ability of elastin stains to improve VI detection is now recognized in …

[HTML][HTML] Prostate gland biopsies and prostatectomies: an Ontario community hospital experience

KJ Newell, JF Amrhein, RJ Desai… - Canadian Urological …, 2008 - ncbi.nlm.nih.gov
Objective Transrectal ultrasound–guided core biopsies of the prostate gland and prostatectomies
have become common procedures at many community hospitals in Canada, especially …