[PDF][PDF] A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
The combined activity of three transcription factors can reprogram adult cells into induced
pluripotent stem cells (iPSCs). However, the transgenic methods used for delivering …
pluripotent stem cells (iPSCs). However, the transgenic methods used for delivering …
Antipsychotic drug use and mortality in older adults with dementia
…, GM Anderson, K Sykora, K Lam… - Annals of internal …, 2007 - acpjournals.org
Background: Antipsychotic drugs are widely used to manage behavioral and psychological
symptoms in dementia despite concerns about their safety. Objective: To examine the …
symptoms in dementia despite concerns about their safety. Objective: To examine the …
Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation
A major obstacle for the discovery of psychoactive drugs is the inability to predict how small
molecules will alter complex behaviors. We report the development and application of a high-…
molecules will alter complex behaviors. We report the development and application of a high-…
A small molecule that directs differentiation of human ESCs into the pancreatic lineage
Stepwise differentiation from embryonic stem cells (ESCs) to functional insulin-secreting
beta cells will identify key steps in beta-cell development and may yet prove useful for …
beta cells will identify key steps in beta-cell development and may yet prove useful for …
Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome
Objective Faecal microbiota transplantation (FMT) is effective for the treatment of recurrent
Clostridium difficile infection (CDI). Studies have shown bacterial colonisation after FMT, but …
Clostridium difficile infection (CDI). Studies have shown bacterial colonisation after FMT, but …
HBsAg seroclearance further reduces hepatocellular carcinoma risk after complete viral suppression with nucleos (t) ide analogues
Background & Aims In treated patients with chronic hepatitis B (CHB) who have achieved
complete viral suppression, it is unclear if functional cure as indicated by hepatitis B surface …
complete viral suppression, it is unclear if functional cure as indicated by hepatitis B surface …
[HTML][HTML] Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection
Fecal microbiota transplantation (FMT) is effective in treating recurrent Clostridium difficile
infection (CDI). Bacterial colonization in recipients after FMT has been studied, but little is …
infection (CDI). Bacterial colonization in recipients after FMT has been studied, but little is …
[HTML][HTML] Describing the linkages of the immigration, refugees and citizenship Canada permanent resident data and vital statistics death registry to Ontario's …
M Chiu, M Lebenbaum, K Lam, N Chong… - BMC medical informatics …, 2016 - Springer
Background Ontario, the most populous province in Canada, has a universal healthcare
system that routinely collects health administrative data on its 13 million legal residents that is …
system that routinely collects health administrative data on its 13 million legal residents that is …
Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication
JP Annes, JH Ryu, K Lam, PJ Carolan… - Proceedings of the …, 2012 - National Acad Sciences
Diabetes is a pathological condition characterized by relative insulin deficiency, persistent
hyperglycemia, and, consequently, diffuse micro- and macrovascular disease. One …
hyperglycemia, and, consequently, diffuse micro- and macrovascular disease. One …
Mental health service use among children and youth in Ontario: population-based trends over time
S Gandhi, M Chiu, K Lam, JC Cairney… - The Canadian …, 2016 - journals.sagepub.com
Objective: Little is known about mental health service use among Canadian children and
youth. Our objective was to examine temporal trends in mental health service use across …
youth. Our objective was to examine temporal trends in mental health service use across …