[HTML][HTML] SARS-CoV-2 infection and transmission in the North American deer mouse
…, AT Duggan, E Moffat, S He, L Garnett, KN Tran… - Nature …, 2021 - nature.com
Widespread circulation of SARS-CoV-2 in humans raises the theoretical risk of reverse
zoonosis events with wildlife, reintroductions of SARS-CoV-2 into permissive nondomesticated …
zoonosis events with wildlife, reintroductions of SARS-CoV-2 into permissive nondomesticated …
[HTML][HTML] Nasal delivery of an adenovirus-based vaccine bypasses pre-existing immunity to the vaccine carrier and improves the immune response in mice
Pre-existing immunity to human adenovirus serotype 5 (Ad5) is common in the general
population. Bypassing pre-existing immunity could maximize Ad5 vaccine efficacy. Vaccination …
population. Bypassing pre-existing immunity could maximize Ad5 vaccine efficacy. Vaccination …
Infectivity of severe acute respiratory syndrome coronavirus 2 in children compared with adults
BACKGROUND: The role of children in the transmission and community spread of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear. We aimed to quantify the …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear. We aimed to quantify the …
[HTML][HTML] Enhanced protection against Ebola virus mediated by an improved adenovirus-based vaccine
JS Richardson, MK Yao, KN Tran, MA Croyle… - PloS one, 2009 - journals.plos.org
Background The Ebola virus is transmitted by direct contact with bodily fluids of infected
individuals, eliciting death rates as high as 90% among infected humans. Currently, replication …
individuals, eliciting death rates as high as 90% among infected humans. Currently, replication …
[HTML][HTML] DNA vaccination protects mice against Zika virus-induced damage to the testes
…, MA De La Vega, J Piret, S Kucas, KN Tran… - Nature …, 2017 - nature.com
Zika virus (ZIKV) is an emerging pathogen causally associated with serious sequelae in
fetuses, inducing fetal microcephaly and other neurodevelopment defects. ZIKV is primarily …
fetuses, inducing fetal microcephaly and other neurodevelopment defects. ZIKV is primarily …
[HTML][HTML] Comparison analysis of different swabs and transport mediums suitable for SARS-CoV-2 testing following shortages
L Garnett, A Bello, KN Tran, J Audet, A Leung… - Journal of virological …, 2020 - Elsevier
On March 11, 2020, the World Health Organization (WHO) assessed COVID-19, caused by
SARS-CoV-2, as a pandemic. As of June 1, 2020, SARS-CoV-2 has had a documented effect …
SARS-CoV-2, as a pandemic. As of June 1, 2020, SARS-CoV-2 has had a documented effect …
In vitro inactivation of SARS-CoV-2 using gamma radiation
A Leung, K Tran, J Audet, S Lavineway, N Bastien… - Applied …, 2020 - liebertpub.com
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is classified
as a Risk Group 3 pathogen; propagative work with this live virus should be conducted in …
as a Risk Group 3 pathogen; propagative work with this live virus should be conducted in …
Protective efficacy and long-term immunogenicity in cynomolgus macaques by Ebola virus glycoprotein synthetic DNA vaccines
…, S Jones, A Bello, G Soule, KN Tran… - The Journal of …, 2019 - academic.oup.com
Background There remains an important need for prophylactic anti-Ebola virus vaccine
candidates that elicit long-lasting immune responses and can be delivered to vulnerable …
candidates that elicit long-lasting immune responses and can be delivered to vulnerable …
Mucosal delivery of adenovirus-based vaccine protects against Ebola virus infection in mice
Background. Mucosal vaccination can offer several advantages over conventional
intramuscular immunization to protect against Ebola virus (EBOV) infection, such as immune …
intramuscular immunization to protect against Ebola virus (EBOV) infection, such as immune …
Impact of systemic or mucosal immunity to adenovirus on Ad-based Ebola virus vaccine efficacy in guinea pigs
JS Richardson, MC Abou, KN Tran… - The Journal of …, 2011 - academic.oup.com
Background. Approximately 35% of the North American population and an estimated 90%
of the sub-Saharan African population have antibodies against adenovirus serotype 5 (AdHu5…
of the sub-Saharan African population have antibodies against adenovirus serotype 5 (AdHu5…