ContextNeuropsychiatric symptoms of dementia are common and associated with poor
outcomes for patients and caregivers. Although nonpharmacological interventions should be the …

This review summarizes evidence from studies of blood pressure and dementia-related
biomarkers into our understanding of cognitive health and highlights the challenges facing …

Importance In older adults reduced mobility is common and is an independent risk factor for
morbidity, hospitalization, disability, and mortality. Limited evidence suggests that physical …

Importance The appropriate treatment target for systolic blood pressure (SBP) in older
patients with hypertension remains uncertain. Objective To evaluate the effects of intensive (<120 …

Importance There are currently no proven treatments to reduce the risk of mild cognitive
impairment and dementia. Objective To evaluate the effect of intensive blood pressure control on …

Background: High blood pressure is an important public health concern because it is highly
prevalent and a risk factor for adverse health outcomes, including coronary heart disease, …

Importance Epidemiological evidence suggests that physical activity benefits cognition, but
results from randomized trials are limited and mixed. Objective To determine whether a 24-…

… Kaycee Sink were responsible for the conception and design of the study. Jayna Holroyd-Leduc,
Kaycee Sink … Kaycee Sink and Farah Khandwala critically revised the article. All of the …

The appropriate target for BP in patients with CKD and hypertension remains uncertain. We
report prespecified subgroup analyses of outcomes in participants with baseline CKD in the …

Context The herbal product Ginkgo biloba is taken frequently with the intention of improving
cognitive health in aging. However, evidence from adequately powered clinical trials is …