Background Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors
have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses …

Background. A common feature of most reviews or catalogues of health utilities has been their
focus on adult health states or derivation of values from adult populations. More generally, …

Purpose Whole-exome (WES) and whole-genome sequencing (WGS) increase the diagnostic
yield in autism spectrum disorder (ASD) compared to chromosomal microarray (CMA), but …

Background Childhood illness can impose significant costs and health strains on family
members, but these are not routinely captured by pediatric economic evaluations. This review …

Purpose To systematically assess patterns and temporal changes in the measurement and
valuation of childhood health utilities and associations between methodological factors. …

This study measured resource utilization and costs for pre-school autism spectrum disorder (ASD)-related
services in community-based sectors from multiple payer perspectives in two …

The clinical use of whole-genome sequencing (WGS) is expected to alter pediatric medical
management. The study aimed to describe the type and cost of healthcare activities following …

Genome sequencing (GS) is increasingly being translated into clinical practice and is a
technology characterized by a complex multi-step workflow. Funding decisions for GS would be …

Background: Genome-wide sequencing has emerged as a promising strategy for the timely
diagnosis of rare diseases, but it is not yet available as a clinical test performed in Canadian …

Background Parent coaching interventions for young children suspected of having autism
spectrum disorder (ASD) have shown promise. The objectives were to measure the costs of …