Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced …
…, K Patel, RR Robinson… - Neuro-Oncology …, 2023 - academic.oup.com
Background Serclutamab talirine (Ser-T, formerly ABBV-321) is an antibody-drug conjugate
consisting of an antibody (AM-1-ABT-806) directed against activated epidermal growth factor …
consisting of an antibody (AM-1-ABT-806) directed against activated epidermal growth factor …
Treatment with didemnin B, an elongation factor 1A inhibitor, improves hepatic lipotoxicity in obese mice
…, DL Robson, R Arya, K Kelly… - Physiological …, 2016 - Wiley Online Library
Eukaryotic elongation factor EEF 1A1 is induced by oxidative and ER stress, and contributes
to subsequent cell death in many cell types, including hepatocytes. We recently showed …
to subsequent cell death in many cell types, including hepatocytes. We recently showed …
Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non–small-cell lung cancer …
K Kelly, K Chansky, LE Gaspar, KS Albain… - Journal of clinical …, 2008 - ascopubs.org
Purpose Early clinical studies with gefitinib showed promising efficacy and mild toxicity in
patients with advanced non–small-cell lung cancer (NSCLC). Thus, gefitinib was an ideal …
patients with advanced non–small-cell lung cancer (NSCLC). Thus, gefitinib was an ideal …
Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade
The recent successes of immunotherapy have shifted the paradigm in cancer treatment, but
because only a percentage of patients are responsive to immunotherapy, it is imperative to …
because only a percentage of patients are responsive to immunotherapy, it is imperative to …
[HTML][HTML] A low-glycemic index diet and exercise intervention reduces TNFα in isolated mononuclear cells of older, obese adults
KR Kelly, JM Haus, TPJ Solomon, AJ Patrick-Melin… - The Journal of …, 2011 - Elsevier
Low-glycemic index diets and exercise independently improve glucose tolerance and reduce
diabetes risk. However, the combined effect of a low-glycemic index diet and exercise on …
diabetes risk. However, the combined effect of a low-glycemic index diet and exercise on …
Nivolumab plus ipilimumab vs nivolumab for previously treated patients with stage IV squamous cell lung cancer: the lung-MAP S1400I phase 3 randomized clinical …
…, VA Papadimitrakopoulou, K Kelly… - JAMA …, 2021 - jamanetwork.com
Importance Nivolumab plus ipilimumab is superior to platinum-based chemotherapy in
treatment-naive advanced non–small cell lung cancer (NSCLC). Nivolumab is superior to …
treatment-naive advanced non–small cell lung cancer (NSCLC). Nivolumab is superior to …
[HTML][HTML] Risk factors for musculoskeletal injuries in the military: a qualitative systematic review of the literature from the past two decades and a new prioritizing injury …
Background Musculoskeletal injuries (MSkIs) are a leading cause of health care utilization,
as well as limited duty and disability in the US military and other armed forces. MSkIs affect …
as well as limited duty and disability in the US military and other armed forces. MSkIs affect …
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts
…, JM Rembetsy-Brown, K Kelly… - Nucleic Acids …, 2022 - academic.oup.com
The lung is a complex organ with various cell types having distinct roles. Antisense oligonucleotides
(ASOs) have been studied in the lung, but it has been challenging to determine their …
(ASOs) have been studied in the lung, but it has been challenging to determine their …
Night shift
KK Robson - CMAJ, 2005 - Can Med Assoc
Everything seemed backward to me when I started working night shifts: it was dark, and I was
awake. I looked upon it as if I were the captain of a ship, ferrying patients from night to light, …
awake. I looked upon it as if I were the captain of a ship, ferrying patients from night to light, …
[HTML][HTML] The benefit of mental skills training on performance and stress response in military personnel
…, JT Jameson, DC Johnson, KR Kelly - Frontiers in …, 2020 - frontiersin.org
Mental skills training (MST) has been suggested to reduce stress in civilian and athletic
populations, however, whether these techniques and practices transfer to a military population …
populations, however, whether these techniques and practices transfer to a military population …
