3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain
…, Y Ogasawara, T Togawa, K Ishii… - Antioxidants & redox …, 2009 - liebertpub.com
Hydrogen sulfide (H 2 S) is a synaptic modulator as well as a neuroprotectant. Currently,
pyridoxal-5′-phosphate (PLP)-dependent cystathionine β-synthase (CBS) is thought to be the …
pyridoxal-5′-phosphate (PLP)-dependent cystathionine β-synthase (CBS) is thought to be the …
[PDF][PDF] Host innate immune receptors and beyond: making sense of microbial infections
The complexity of the immune system mirrors its manifold mechanisms of host-microbe
interactions. A relatively simplified view was posited after the identification of host innate immune …
interactions. A relatively simplified view was posited after the identification of host innate immune …
Innate immune response to viral infection
In viral infections the host innate immune system is meant to act as a first line defense to
prevent viral invasion or replication before more specific protection by the adaptive immune …
prevent viral invasion or replication before more specific protection by the adaptive immune …
First results from KamLAND: evidence for reactor antineutrino disappearance
…, H Hanada, H Ikeda, K Ikeda, K Inoue, K Ishihara… - Physical review …, 2003 - APS
KamLAND has measured the flux of ν e’s from distant nuclear reactors. We find fewer ν e
events than expected from standard assumptions about ν e propagation at the 99.95% CL In a …
events than expected from standard assumptions about ν e propagation at the 99.95% CL In a …
Measurement of neutrino oscillation with KamLAND: Evidence of spectral distortion
…, K Furuno, K Ichimura, H Ikeda, K Inoue, K Ishihara… - Physical review …, 2005 - APS
We present results of a study of neutrino oscillation based on a 766 ton/year exposure of
KamLAND to reactor antineutrinos. We observe 258 ν e candidate events with energies above …
KamLAND to reactor antineutrinos. We observe 258 ν e candidate events with energies above …
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
…, K Matsui, S Uematsu, A Jung, T Kawai, KJ Ishii… - Nature, 2006 - nature.com
The innate immune system senses viral infection by recognizing a variety of viral
components (including double-stranded (ds)RNA) and triggers antiviral responses 1 , 2 . The …
components (including double-stranded (ds)RNA) and triggers antiviral responses 1 , 2 . The …
The DNA sequence of human chromosome 21
…, H Watanabe, T Yada, HS Park, A Toyoda, K Ishii… - Nature, 2000 - nature.com
Chromosome 21 is the smallest human autosome. An extra copy of chromosome 21 causes
Down syndrome, the most frequent genetic cause of significant mental retardation, which …
Down syndrome, the most frequent genetic cause of significant mental retardation, which …
High performance plasma amyloid-β biomarkers for Alzheimer's disease
…, K Ishii, K Ishii, Y Arahata, S Iwamoto, K Ito, K Tanaka… - Nature, 2018 - nature.com
To facilitate clinical trials of disease-modifying therapies for Alzheimer’s disease, which are
expected to be most efficacious at the earliest and mildest stages of the disease 1 , 2 , …
expected to be most efficacious at the earliest and mildest stages of the disease 1 , 2 , …
IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction
Type I interferons are central mediators for antiviral responses. Using high-throughput functional
screening of interferon inducers, we have identified here a molecule we call interferon-β …
screening of interferon inducers, we have identified here a molecule we call interferon-β …
Physicochemical properties and structures of room temperature ionic liquids. 2. Variation of alkyl chain length in imidazolium cation
H Tokuda, K Hayamizu, K Ishii… - The Journal of …, 2005 - ACS Publications
… where N A is the Avogadro number, e is the electric charge on each ionic carrier, k in the
Boltzmann constant, F is the Faraday constant, and R is the gas constant. Figure 5b shows the …
Boltzmann constant, F is the Faraday constant, and R is the gas constant. Figure 5b shows the …