Background. Mycobacterium abscessus can produce a chronic pulmonary infection for
which little is known regarding optimal treatment and long-term outcomes. Methods. We …

Background Data from Kwazulu Natal, South Africa, suggest that almost all patients with
extensively drug-resistant (XDR) tuberculosis are HIV-positive, with a fatal outcome. Since, there …

Background: Nosocomial transmission has been described in extensively drug-resistant
tuberculosis (XDR-TB) and HIV co-infected patients in South Africa. However, little is known …

Background Mycobacterium avium complex (MAC) lung disease requires prolonged treatment
with multiple antibiotics. Drug intolerances and interactions are common with the current …

Despite the development of effective treatments, tuberculosis (TB) remains a major health
problem. TB continues to infect new victims and kills nearly 2 million people annually. The …

Nontuberculous mycobacteria (NTM) are diverse microbial species encompassing commensals
and pathogens with the ability to cause pulmonary disease in both immunocompetent …

Adverse events are frequent in nontuberculous mycobacteria pulmonary disease treatment,
but evidence to support their management is scarce. An expert panel survey on …

The use of anti-tumor necrosis factor-a (TNF-a) therapies has led to improved outcomes in
the treatment of rheumatoid arthritis (RA). However, the use of these new therapeutic agents …

Objective To determine the clinical profile and outcomes of health care workers (HCWs)
with extensively drug resistant tuberculosis (XDR‐TB) in the Eastern and Western Cape …

Fig. 2: Chest CT scan showing an irregular hyperdense mass in the right upper lobe.
interstitial inflammation (Fig. 3). There was no evidence of malignant disease. Transmission …