Background Some people with substantial Alzheimer's disease pathology at autopsy had
shown few characteristic clinical symptoms or signs of the disease, whereas others with little …

Background Parallel to growth of aging and obese populations, the prevalence of metabolic
diseases is rising. How body mass index (BMI) relates to frailty and mortality across frailty …

Background Beyond intakes of total energy and individual nutrient, eating patterns may
influence health, and thereby the risk of adverse outcomes. How different diet measures relate to …

BACKGROUND: Sedentary behaviours are associated with adverse health outcomes in
middle-aged and older adults, even among those who exercise. We examined whether the …

Background/objectives Influenza is associated with significant morbidity and mortality,
particularly for older adults. Persistent functional decline following hospitalization has important …

Background frailty is a public health priority now that the global population is ageing at a
rapid rate. A scientifically sound tool to measure frailty and generate population-based …

Background We examined frailty as a predictor of recovery in older adults hospitalized with
influenza and acute respiratory illness. Methods A total of 5011 patients aged ≥65 years …

Background Clinically meaningful change (CMC) for frailty index (FI) scores is little studied.
We estimated the CMC by associating changes in FI scores with changes in the Clinical …

Background: Frailty has been considered an antecedent and, to a lesser extent, an outcome
of cognitive impairment. Both frailty and cognitive impairment are multiply determined and …

Objectives Despite their role in health and disease, the relationship between fatty acids (FAs)
and frailty and mortality remains unclear. The aim of this study was to explore how FA …