Objective To update the 2006 Canadian guidelines for primary care of adults with developmental
disabilities (DD) and to make practical recommendations based on current knowledge …

OBJECTIVE To develop practical Canadian guidelines for primary health care providers based
on the best available evidence for addressing health issues in adults with developmental …

We have attempted to identify published descriptions and reports of skeletal remains, figurines
and paintings of suggested or supposed instances of Down syndrome predating John …

• Five new cases are presented of a syndrome characterized mainly by severe mental
retardation, epilepsy, puppet-like ataxic movements, microbrachycephaly, prognathism, tongue …

A severely retarded epileptic, microbrachycephalic child, had an ataxic puppet-like gait and
a proneness to uncontrollable paroxysms of laughter. These and additional abnormalities …

We previously observed low level mosaicism (2–4% normal cells) in phytohemagglutinin‐stimulated
peripheral blood lymphocytes (PBL) in 29% of a small group of elderly persons with …

We have identified 2 sisters with probable dementia of the Alzheimer type who have an
unusual 22‐derived marker chromosome with a greatly elongated short arm containing 2 well‐…

In detailed published accounts to date of 40 twin pairs one or both of whom were said to have
Alzheimer's disease (AD), 16 of 35 monozygotic (MZ) pairs were described as concordant …

Platelet 3 H-imipramine binding in 12 subjects with Down's syndrome showed a significantly
lower maximal number of binding sites (B max ) as compared to both unrelated normal and …

In this Policy Statement, we delineate the recommended resources necessary to prepare
emergency departments (EDs) to care for pediatric patients. Adoption of the recommendations …