Context Infection is a major cause of morbidity and mortality in intensive care units (ICUs)
worldwide. However, relatively little information is available about the global epidemiology of …

Background. Morbidity and mortality for critically ill patients with infections remains a global
healthcare problem. We aimed to determine whether β-lactam antibiotic dosing in critically ill …

Objectives To evaluate risk factors for ventilator-associated pneumonia (VAP), as well as its
influence on in-hospital mortality, resource utilization, and hospital charges. Design …

Objective: To determine whether continuous subglottic aspiration prevents nosocomial
pneumonia in mechanically ventilated patients. Design: A randomized, controlled, blinded study. …

In order to assess potential risk factors for pneumonia within the first 8 d of ventilation, we
studied 83 consecutive intubated patients undergoing continuous aspiration of subglottic …

The use of microbiologic investigations in routine clinical practice, their value in guiding
antibiotic prescription, and their influence on outcome were prospectively studied in 113 …

Introduction Patients with influenza A (H1N1)v infection have developed rapidly progressive
lower respiratory tract disease resulting in respiratory failure. We describe the clinical and …

Design: The objectives were to characterize the prognostic factors and evaluate the impact
of inappropriate empiric antibiotic treatment and systemic response on the outcome of …

Objective To assess the effect of baseline variables, including treatment, on outcome in patients
with nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA). …

Introduction Human host immune response following infection with the new variant of A/H1N1
pandemic influenza virus (nvH1N1) is poorly understood. We utilize here systemic …