[HTML][HTML] Normothermic ex vivo lung perfusion in clinical lung transplantation
Background More than 80% of donor lungs are potentially injured and therefore not considered
suitable for transplantation. With the use of normothermic ex vivo lung perfusion (EVLP), …
suitable for transplantation. With the use of normothermic ex vivo lung perfusion (EVLP), …
Technique for prolonged normothermic ex vivo lung perfusion
M Cypel, JC Yeung, S Hirayama, M Rubacha… - The Journal of heart and …, 2008 - Elsevier
BACKGROUND: The inhibition of cellular metabolism induced by hypothermia obviates the
possibility of substantial reparative processes occurring during organ preservation. The aim …
possibility of substantial reparative processes occurring during organ preservation. The aim …
[HTML][HTML] Experience with the first 50 ex vivo lung perfusions in clinical transplantation
OBJECTIVE: Normothermic ex vivo lung perfusion is a novel method to evaluate and improve
the function of injured donor lungs. We reviewed our experience with 50 consecutive …
the function of injured donor lungs. We reviewed our experience with 50 consecutive …
Functional repair of human donor lungs by IL-10 gene therapy
More than 80% of potential donor lungs are injured during brain death of the donor and
from complications experienced in the intensive care unit, and therefore cannot be used for …
from complications experienced in the intensive care unit, and therefore cannot be used for …
Functional Production and Characterization of a Fibrin-Specific Single-Chain Antibody Fragment from Bacillus subtilis: Effects of Molecular Chaperones and a Wall …
SC Wu, JC Yeung, Y Duan, R Ye… - Applied and …, 2002 - Am Soc Microbiol
… Jonathan C. Yeung was supported in part by summer studentships from both Alberta
Heritage Foundation of Medical Research (AHFMR) and Natural Science and Engineering …
Heritage Foundation of Medical Research (AHFMR) and Natural Science and Engineering …
Physiologic assessment of the ex vivo donor lung for transplantation
JC Yeung, M Cypel, TN Machuca, T Koike… - The Journal of Heart and …, 2012 - Elsevier
… Author links open overlay panel Jonathan C. Yeung MD, PhD a , Marcelo Cypel MD a ,
Tiago N. Machuca MD, PhD a , Terumoto Koike MD, PhD a , Douglas J. Cook MD, PhD a , …
Tiago N. Machuca MD, PhD a , Terumoto Koike MD, PhD a , Douglas J. Cook MD, PhD a , …
Outcomes after transplantation of lungs preserved for more than 12 h: a retrospective study
JC Yeung, T Krueger, K Yasufuku… - The Lancet …, 2017 - thelancet.com
Background Ex-vivo lung perfusion (EVLP) can be used to extend overall lung preservation
time by splitting one long cold ischaemic time into two shorter ones and interposing an …
time by splitting one long cold ischaemic time into two shorter ones and interposing an …
Long-term outcomes of lung transplant with ex vivo lung perfusion
…, M de Perrot, A Pierre, K Yasufuku, JC Yeung… - JAMA …, 2019 - jamanetwork.com
Importance The mortality rate for individuals on the wait list for lung transplant is 15% to 25%,
and still only 20% of lungs from multiorgan donors are used for lung transplant. The lung …
and still only 20% of lungs from multiorgan donors are used for lung transplant. The lung …
[HTML][HTML] Extracorporeal life support as a bridge to lung transplantation–experience of a high-volume transplant center
Objectives Extracorporeal life support (ECLS) is increasingly used to bridge deteriorating
patients awaiting lung transplantation (LTx), however, few systematic descriptions of this …
patients awaiting lung transplantation (LTx), however, few systematic descriptions of this …
[HTML][HTML] Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre-and post–lung transplantation in the pig
JC Yeung, D Wagnetz, M Cypel, M Rubacha, T Koike… - Molecular Therapy, 2012 - cell.com
Acellular normothermic ex vivo lung perfusion (EVLP) is a novel method of donor lung
preservation for transplantation. As cellular metabolism is preserved during perfusion, it …
preservation for transplantation. As cellular metabolism is preserved during perfusion, it …