APTAMERS 1 are double-stranded DNA or single-stranded RNA molecules that bind specific
molecular targets. Large randomly generated populations can be enriched in aptamers by …

A complete copy of the mRNA sequences encoding human coagulation factor VIII:C has
been cloned and expressed. The DNA sequence predicts a single chain precursor of 2,351 …

ContextTenofovir disoproxil fumarate (DF) is a once-daily nucleotide analogue reverse
transcriptase inhibitor.ObjectiveTo evaluate the efficacy and safety of tenofovir DF compared with …

Background Durable suppression of replication of the human immunodeficiency virus (HIV)
depends on the use of potent, well-tolerated antiretroviral regimens to which patients can …

Fine- and microstructure data from a free fall profiler are analysed to test models that relate
the turbulent dissipation rate (ε) to characteristics of the internal wave field. The data were …

cDNA clones encoding human factor V have been isolated from an oligo(dT)-primed human
fetal liver cDNA library prepared with vector Charon 21A. The cDNA sequence of factor V …

Factor VIII (antihemophilic factor) is a high molecular weight plasma glycoprotein that participates
in the blood clotting cascade. The recent cloning and sequence analysis of the cDNA …

We investigate basin‐scale mechanisms regulating anomalies in freshwater content (FWC)
in the Beaufort Gyre (BG) of the Arctic Ocean using historical observations and data collected …

Abstract Analysis of modern and historical observations demonstrates that the temperature
of the intermediate-depth (150–900 m) Atlantic water (AW) of the Arctic Ocean has increased …

Using a novel in vitro selection/amplification technique, we have recently identified a new
class of thrombin inhibitors based on single- stranded DNA oligonucleotides. One …