[HTML][HTML] Powassan encephalitis: a case report with neuropathology and literature review
BIA Gholam, S Puksa, JP Provias - CMAJ, 1999 - Can Med Assoc
CMAJ• NOV. 30, 1999; 161 (11) 1419 nation showed mild diffuse swelling of the cerebral
hemispheres with diffuse meningeal congestion. Histological examination revealed an intense …
hemispheres with diffuse meningeal congestion. Histological examination revealed an intense …
The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers
Glioblastoma (GBM) is characterized by extensive cellular and genetic heterogeneity. Its
initial presentation as primary disease (pGBM) has been subject to exhaustive molecular and …
initial presentation as primary disease (pGBM) has been subject to exhaustive molecular and …
[HTML][HTML] Wnt activation as a therapeutic strategy in medulloblastoma
…, N Winegarden, R Hallett, JP Provias… - Nature …, 2020 - nature.com
Medulloblastoma (MB) is defined by four molecular subgroups (Wnt, Shh, Group 3, Group 4)
with Wnt MB having the most favorable prognosis. Since prior reports have illustrated the …
with Wnt MB having the most favorable prognosis. Since prior reports have illustrated the …
Pyrvinium targets CD133 in human glioblastoma brain tumor–initiating cells
…, N Garg, T Vijayakumar, B Lach, JP Provias… - Clinical Cancer …, 2015 - AACR
Purpose: Clonal evolution of cancer may be regulated by determinants of stemness, specifically
self-renewal, and current therapies have not considered how genetic perturbations or …
self-renewal, and current therapies have not considered how genetic perturbations or …
A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells
…, M Subapanditha, N Savage, N Tatari, JP Provias… - Oncogene, 2020 - nature.com
Mechanistic insight into signaling pathways downstream of surface receptors has been
revolutionized with integrated cancer genomics. This has fostered current treatment modalities, …
revolutionized with integrated cancer genomics. This has fostered current treatment modalities, …
A cancer stem cell model for studying brain metastases from primary lung cancer
…, P Klurfan, E Kachur, JP Provias… - Journal of the …, 2013 - academic.oup.com
Background Brain metastases are most common in adults with lung cancer, predicting
uniformly poor patient outcome, with a median survival of only months. Despite their frequency …
uniformly poor patient outcome, with a median survival of only months. Despite their frequency …
Congenital brain tumors: diagnostic pitfalls and therapeutic interventions
B Manoranjan, JP Provias - Journal of Child Neurology, 2011 - journals.sagepub.com
Congenital brain tumors are rare, accounting for 0.5% to 4% of all pediatric brain tumors. A
10-year retrospective study based on autopsy and neurosurgical clinical reports with a …
10-year retrospective study based on autopsy and neurosurgical clinical reports with a …
[HTML][HTML] Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells
…, N Murty, J Kwiecien, F Farrokhyar, JP Provias… - Stem cell …, 2012 - Elsevier
The master regulatory gene Bmi1 modulates key stem cell properties in neural precursor
cells (NPCs), and has been implicated in brain tumorigenesis. We previously identified a …
cells (NPCs), and has been implicated in brain tumorigenesis. We previously identified a …
Cadmium encephalopathy: a report with elemental analysis and pathological findings
JP Provias, CA Ackerley, C Smith, LE Becker - Acta neuropathologica, 1994 - Springer
We report a boy of East Indian origin, aged 2 years and 10 months, who died suddenly and
unexpectedly. Autopsy findings showed marked cerebral swelling with herniation and …
unexpectedly. Autopsy findings showed marked cerebral swelling with herniation and …
[HTML][HTML] The identification of human pituitary adenoma-initiating cells
…, A Algird, NK Murty, DD Sommer, JP Provias… - Acta Neuropathologica …, 2016 - Springer
Classified as benign central nervous system (CNS) tumors, pituitary adenomas account for
10% of diagnosed intracranial neoplasms. Although surgery is often curative, patients with …
10% of diagnosed intracranial neoplasms. Although surgery is often curative, patients with …