Non-melanoma skin cancer
V Madan, JT Lear, RM Szeimies - The lancet, 2010 - thelancet.com
The rising incidence and morbidity of non-melanoma skin cancers has generated great
interest in unravelling of their pathogenesis and in the search for new non-invasive treatments. …
interest in unravelling of their pathogenesis and in the search for new non-invasive treatments. …
Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind …
…, R Plummer, ALS Chang, F Cornélis, JT Lear… - The Lancet …, 2015 - thelancet.com
Background Patients with advanced basal cell carcinoma have limited treatment options.
Hedgehog pathway signalling is aberrantly activated in around 95% of tumours. We assessed …
Hedgehog pathway signalling is aberrantly activated in around 95% of tumours. We assessed …
Association between functional polymorphism in EGF gene and malignant melanoma
…, RC Strange, PE Hutchinson, JE Osborne, JT Lear… - The Lancet, 2002 - thelancet.com
Background Malignant melanoma, the most serious cutaneous malignancy, has attracted
substantial attention because of its rapidly increasing incidence and the poor prognosis of …
substantial attention because of its rapidly increasing incidence and the poor prognosis of …
[BOOK][B] Workers, Neighbors, and Citizens: The Revolution in Mexico City
J Lear - 2001 - books.google.com
… John Lear addresses a basic paradox: During one of the great … ř Lear identifies a significant
and largely underestimated tradition … Lear suggests that the prominence of labor after the …
and largely underestimated tradition … Lear suggests that the prominence of labor after the …
Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma
PE Hutchinson, JE Osborne, JT Lear, AG Smith… - Clinical Cancer …, 2000 - AACR
Calcitriol[1,25(OH) 2 D 3 ], the hormonal derivative of vitamin D 3 , is an antiproliferative and
prodifferentiation factor for several cell types, including cultured melanocytes and malignant …
prodifferentiation factor for several cell types, including cultured melanocytes and malignant …
[HTML][HTML] The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): a phase II, randomized, double-blind study of sonidegib in …
…, F Cornélis, R Kudchadkar, U Trefzer, JT Lear… - Journal of the American …, 2016 - Elsevier
Background The hedgehog pathway inhibitor sonidegib demonstrated meaningful tumor
shrinkage in more than 90% of patients with locally advanced basal cell carcinoma (BCC) or …
shrinkage in more than 90% of patients with locally advanced basal cell carcinoma (BCC) or …
British Association of Dermatologists guidelines for the management of adults with basal cell carcinoma 2021
…, G Gupta, M Hashme, S Hoey, JT Lear… - British Journal of …, 2021 - academic.oup.com
British Association of Dermatologists guidelines for the management of adults with basal cell
carcinoma 2021* | British Journal of Dermatology | Oxford Academic Skip to Main Content …
carcinoma 2021* | British Journal of Dermatology | Oxford Academic Skip to Main Content …
[HTML][HTML] Non-melanoma skin cancer
Non-melanoma skin cancer (NMSC) comprises basal cell carcinoma (BCC) and squamous
cell carcinoma, together with a host of rare tumours. NMSC is the commonest malignancy …
cell carcinoma, together with a host of rare tumours. NMSC is the commonest malignancy …
[HTML][HTML] Emerging trends in the treatment of advanced basal cell carcinoma
Basal cell carcinoma (BCC) is the most commonly diagnosed skin cancer worldwide. In most
patients, BCC can be effectively treated with standard surgical excision, Mohs micrographic …
patients, BCC can be effectively treated with standard surgical excision, Mohs micrographic …
Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors
TJ Lovatt, JT Lear, J Bastrilles, C Wong… - Journal of the American …, 2005 - Elsevier
BACKGROUND: Patients with basal cell carcinoma (BCC) frequently develop further tumors
during follow-up. OBJECTIVE: We sought to elucidate the relative effects of pattern of …
during follow-up. OBJECTIVE: We sought to elucidate the relative effects of pattern of …