Purpose To determine the clinical utility of intrinsic molecular phenotype after breast-
conserving therapy (BCT) with lumpectomy and whole-breast irradiation with or without a …

Prostate cancer (CaP) is the second leading malignancy in men. The role of epithelial cell
adhesion molecule (EpCAM), also known as CD326, in CaP progression and therapeutic …

INTRODUCTION Prostate cancer (CaP) is the second leading malignancy in older men in
Western countries. The role of CD44 variant 6 (CD44v6) in CaP progression and therapeutic …

Radiation therapy (RT) continues to be one of the most popular treatment options for localized
prostate cancer (CaP). Local CaP recurrence after RT is a pattern of treatment failure …

This paper reports the development and application of intralesional targeted alpha therapy (TAT)
for melanoma, being the first part of a program to establish a new systemic therapy. …

Background. Klippel-Feil syndrome (KFS) is characterised by congenital vertebral fusion of
the cervical spine and a wide spectrum of associated anomalies. KFS has often been …

Purpose. The aim is to assess toxicity and response of systemic alpha therapy for metastatic
melanoma. Experimental design. This is an open-labelled Phase 1 dose escalation study to …

Despite significant advances in surgery, radiotherapy and chemotherapy to treat prostate
cancer (CaP), many patients die of secondary disease (metastases). Current therapeutic …

CD44 and CD147 are associated with cancer metastasis and progression. Our purpose in
the study was to investigate the effects of down-regulation of CD44 or CD147 on the …

Purpose : Merkel cell carcinoma (MCC), being a small cell carcinoma, would be expected to
be sensitive to radiation. Clinical analysis of patients at our center, especially those with …