User profiles for John Gillespie

John W Gillespie Jr

University of Delaware
Verified email at udel.edu
Cited by 25272

[BOOK][B] The causes of molecular evolution

JH Gillespie - 1991 - books.google.com
This work provides a unified theory that addresses the important problem of the origin and
maintenance of genetic variation in natural populations. With modern molecular techniques, …

Genotype-environment interactions and the maintenance of polygenic variation.

JH Gillespie, M Turelli - Genetics, 1989 - academic.oup.com
Genotype-environment interactions may be a potent force maintaining genetic variation in
quantitative traits in natural populations. This is shown by a simple model of additive polygenic …

[BOOK][B] Population genetics: a concise guide

JH Gillespie - 2004 - books.google.com
… Addressing the theories behind population genetics and relevant empirical evidence, John
Gillespie discusses genetic drift, natural selection, nonrandom mating, quantitative genetics, …

5‐Aminoimidazole‐4‐carboxamide ribonucleoside: a specific method for activating AMP‐activated protein kinase in intact cells?

JM Corton, JG Gillespie, SA Hawley… - European journal of …, 1995 - Wiley Online Library
The AMP‐activated protein kinase (AMPK) is believed to protect cells against environmental
stress (eg heat shock) by switching off biosynthetic pathways, the key signal being elevation …

Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

…, VE Bichsel, NL Simone, T Chen, JW Gillespie… - Oncogene, 2001 - nature.com
Protein arrays are described for screening of molecular markers and pathway targets in patient
matched human tissue during disease progression. In contrast to previous protein arrays …

Hopkinson bar experimental technique: a critical review

…, SL Lopatnikov, JW Gillespie Jr - Appl. Mech …, 2004 - asmedigitalcollection.asme.org
A critical review of three classic papers by B Hopkinson, RM Davies, and H Kolsky, and the
state-of-the-art in Hopkinson bar experimental techniques is presented. The validity and …

Process-induced stress and deformation in thick-section thermoset composite laminates

TA Bogetti, JW Gillespie Jr - Journal of composite materials, 1992 - journals.sagepub.com
A study of process-induced stress and deformation in thick-section thermosetting composite
laminates is presented. A methodology is proposed for predict ing the evolution of residual …

Carbon nanotube amplification strategies for highly sensitive immunodetection of cancer biomarkers

…, A Bhirde, JD Gong, SN Kim, J Gillespie… - Journal of the …, 2006 - ACS Publications
We describe herein the combination of electrochemical immunosensors using single-wall
carbon nanotube (SWNT) forest platforms with multi-label secondary antibody-nanotube …

Post-analysis follow-up and validation of microarray experiments

RF Chuaqui, RF Bonner, CJM Best, JW Gillespie… - Nature …, 2002 - nature.com
Measurement of gene-expression profiles using microarray technology is becoming
increasingly popular among the biomedical research community. Although there has been great …

Natural selection for variances in offspring numbers: a new evolutionary principle

JH Gillespie - The American Naturalist, 1977 - journals.uchicago.edu
LETTERS TO THE EDITORS 1011 equated with a better adapted genotype and" the best
adapted individuals of a species tend to leave more offspring on the average than do less well …