User profiles for Joel L. Parlow
Joel ParlowProfessor, Queen's University Verified email at queensu.ca Cited by 8078 |
[HTML][HTML] Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery
Background Valdecoxib and its intravenous prodrug parecoxib are used to treat postoperative
pain but may involve risk after coronary-artery bypass grafting (CABG). We conducted a …
pain but may involve risk after coronary-artery bypass grafting (CABG). We conducted a …
[HTML][HTML] Aspirin in patients undergoing noncardiac surgery
…, BM Biccard, CS Meyhoff, JL Parlow… - … England Journal of …, 2014 - Mass Medical Soc
Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …
[HTML][HTML] Tranexamic acid in patients undergoing noncardiac surgery
…, E Duceppe, K Ruetzler, JL Parlow… - … England Journal of …, 2022 - Mass Medical Soc
Background Perioperative bleeding is common in patients undergoing noncardiac surgery.
Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. Methods …
Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. Methods …
Hypoxic pulmonary vasoconstriction: from molecular mechanisms to medicine
…, A Thakrar, LRG Parlow, JD Mewburn, JL Parlow… - Chest, 2017 - Elsevier
Hypoxic pulmonary vasoconstriction (HPV) is a homeostatic mechanism that is intrinsic to
the pulmonary vasculature. Intrapulmonary arteries constrict in response to alveolar hypoxia, …
the pulmonary vasculature. Intrapulmonary arteries constrict in response to alveolar hypoxia, …
[HTML][HTML] Clonidine in patients undergoing noncardiac surgery
…, BM Biccard, CS Meyhoff, JL Parlow… - … England Journal of …, 2014 - Mass Medical Soc
Background Marked activation of the sympathetic nervous system occurs during and after
noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may …
noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may …
Period-dependent associations between hypotension during and for four days after noncardiac surgery and a composite of myocardial infarction and death: a …
Background The relative contributions of intraoperative and postoperative hypotension to
perioperative morbidity remain unclear. We determined the association between hypotension …
perioperative morbidity remain unclear. We determined the association between hypotension …
Hypotension-avoidance versus hypertension-avoidance strategies in noncardiac surgery: an international randomized controlled trial
Background: Among patients having noncardiac surgery, perioperative hemodynamic
abnormalities are associated with vascular complications. Uncertainty remains about what …
abnormalities are associated with vascular complications. Uncertainty remains about what …
Aspirin in patients with previous percutaneous coronary intervention undergoing noncardiac surgery
MM Graham, DI Sessler, JL Parlow… - Annals of internal …, 2018 - acpjournals.org
Background: Uncertainty remains about the effects of aspirin in patients with prior percutaneous
coronary intervention (PCI) having noncardiac surgery. Objective: To evaluate benefits …
coronary intervention (PCI) having noncardiac surgery. Objective: To evaluate benefits …
Body mass index, outcomes, and mortality following cardiac surgery in Ontario, Canada
Background The “obesity paradox” reflects an observed relationship between obesity and
decreased morbidity and mortality, suggesting improved health outcomes for obese individuals…
decreased morbidity and mortality, suggesting improved health outcomes for obese individuals…
[HTML][HTML] High-sensitivity troponin I after cardiac surgery and 30-day mortality
…, MH McGillion, EP Belley-Côté, JL Parlow… - New England journal …, 2022 - Mass Medical Soc
Background Consensus recommendations regarding the threshold levels of cardiac troponin
elevations for the definition of perioperative myocardial infarction and clinically important …
elevations for the definition of perioperative myocardial infarction and clinically important …