We are performing whole-genome sequencing of families with autism spectrum disorder (ASD)
to build a resource (MSSNG) for subcategorizing the phenotypes and underlying genetic …

Fully understanding autism spectrum disorder (ASD) genetics requires whole-genome
sequencing (WGS). We present the latest release of the Autism Speaks MSSNG resource, which …

A genome-scale genetic interaction map was constructed by examining 5.4 million gene-gene
pairs for synthetic genetic interactions, generating quantitative genetic interaction profiles …

The genetic basis of autism spectrum disorder (ASD) is known to consist of contributions from
de novo mutations in variant-intolerant genes. We hypothesize that rare inherited structural …

Virtual Machine (VM) fork is a new cloud computing abstraction that instantaneously clones
a VM into multiple replicas running on different hosts. All replicas share the same initial state, …

A remaining hurdle to whole-genome sequencing (WGS) becoming a first-tier genetic test
has been accurate detection of copy-number variations (CNVs). Here, we used several …

In this study, semi-structured interviews were conducted with 10 NCAA Division I coaches.
The coaches were asked to discuss their experiences coaching specific athletes who made …

Tandem DNA repeats vary in the size and sequence of each unit (motif). When expanded,
these tandem DNA repeats have been associated with more than 40 monogenic disorders 1 . …

BACKGROUND: The Personal Genome Project Canada is a comprehensive public data
resource that integrates whole genome sequencing data and health information. We describe …

Background Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized
by impaired social and communication skills, restricted interests, and repetitive behaviors…