[HTML][HTML] Lymphopenia and risk of infection and infection-related death in 98,344 individuals from a prospective Danish population-based study

M Warny, J Helby, BG Nordestgaard, H Birgens… - PLoS …, 2018 - journals.plos.org
Background Neutropenia increases the risk of infection, but it is unknown if this also applies
to lymphopenia. We therefore tested the hypotheses that lymphopenia is associated with …

[HTML][HTML] Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population

J Helby, BG Nordestgaard, T Benfield… - haematologica, 2017 - ncbi.nlm.nih.gov
In the general population, older age is associated with short leukocyte telomere length and
with high risk of infections. In a recent study of allogeneic hematopoietic cell transplantation …

[HTML][HTML] Arterial and venous thrombosis by high platelet count and high hematocrit: 108 521 individuals from the Copenhagen General Population Study

M Warny, J Helby, HS Birgens, SE Bojesen… - Journal of Thrombosis …, 2019 - Elsevier
Background It is unclear whether high platelet count or high hematocrit predict risk of
thrombosis in individuals from the general population. Objectives We tested the hypothesis that …

Incidental lymphopenia and mortality: a prospective cohort study

M Warny, J Helby, BG Nordestgaard, H Birgens… - Cmaj, 2020 - Can Med Assoc
BACKGROUND: It is unknown if incidental lymphopenia detected in the general population
is associated with higher all-cause and cause-specific mortality. We aimed to identify the …

Asthma, other atopic conditions and risk of infections in 105 519 general population never and ever smokers

J Helby, BG Nordestgaard, T Benfield… - Journal of Internal …, 2017 - Wiley Online Library
Background Individuals with atopic conditions may have increased susceptibility to infections
outside the organs directly affected by their atopic condition. Objective We tested the …

[HTML][HTML] Smoking cessation and the microbiome in induced sputum samples from cigarette smoking asthma patients

C Munck, J Helby, CG Westergaard, C Porsbjerg… - PLoS …, 2016 - journals.plos.org
Asthma is a common disease causing cough, wheezing and shortness of breath. It has been
shown that the lung microbiota in asthma patients is different from the lung microbiota in …

Investigation of leukocyte telomere length and genetic variants in chromosome 5p15. 33 as prognostic markers in lung cancer

L Kachuri, J Helby, SE Bojesen, DC Christiani… - … Biomarkers & Prevention, 2019 - AACR
Background: Lung cancer remains the leading cause of cancer mortality with relatively few
prognostic biomarkers. We investigated associations with overall survival for telomere length (…

[HTML][HTML] Elevated plasma YKL-40 and risk of infectious disease: a prospective study of 94665 individuals from the general population

AD Kjaergaard, J Helby, JS Johansen… - Clinical Microbiology …, 2020 - Elsevier
Objectives YKL-40 is an acute phase protein elevated in patients with infectious and inflammatory
diseases. We tested the hypothesis that baseline elevated YKL-40 is associated with …

Genetic predisposition to long telomeres is associated with increased mortality after melanoma: A study of 2101 melanoma patients from hospital clinics and the …

H Ismail, J Helby, LR Hölmich… - Pigment Cell & …, 2021 - Wiley Online Library
Whether there is an association between measured and genetically predicted telomere
length and melanoma mortality is unclear. We tested the hypothesis that measured and …