[HTML][HTML] Lymphopenia and risk of infection and infection-related death in 98,344 individuals from a prospective Danish population-based study
M Warny, J Helby, BG Nordestgaard, H Birgens… - PLoS …, 2018 - journals.plos.org
Background Neutropenia increases the risk of infection, but it is unknown if this also applies
to lymphopenia. We therefore tested the hypotheses that lymphopenia is associated with …
to lymphopenia. We therefore tested the hypotheses that lymphopenia is associated with …
[HTML][HTML] Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population
J Helby, BG Nordestgaard, T Benfield… - haematologica, 2017 - ncbi.nlm.nih.gov
In the general population, older age is associated with short leukocyte telomere length and
with high risk of infections. In a recent study of allogeneic hematopoietic cell transplantation …
with high risk of infections. In a recent study of allogeneic hematopoietic cell transplantation …
[HTML][HTML] Arterial and venous thrombosis by high platelet count and high hematocrit: 108 521 individuals from the Copenhagen General Population Study
M Warny, J Helby, HS Birgens, SE Bojesen… - Journal of Thrombosis …, 2019 - Elsevier
Background It is unclear whether high platelet count or high hematocrit predict risk of
thrombosis in individuals from the general population. Objectives We tested the hypothesis that …
thrombosis in individuals from the general population. Objectives We tested the hypothesis that …
Incidental lymphopenia and mortality: a prospective cohort study
M Warny, J Helby, BG Nordestgaard, H Birgens… - Cmaj, 2020 - Can Med Assoc
BACKGROUND: It is unknown if incidental lymphopenia detected in the general population
is associated with higher all-cause and cause-specific mortality. We aimed to identify the …
is associated with higher all-cause and cause-specific mortality. We aimed to identify the …
Asthma, other atopic conditions and risk of infections in 105 519 general population never and ever smokers
J Helby, BG Nordestgaard, T Benfield… - Journal of Internal …, 2017 - Wiley Online Library
Background Individuals with atopic conditions may have increased susceptibility to infections
outside the organs directly affected by their atopic condition. Objective We tested the …
outside the organs directly affected by their atopic condition. Objective We tested the …
[HTML][HTML] Smoking cessation and the microbiome in induced sputum samples from cigarette smoking asthma patients
C Munck, J Helby, CG Westergaard, C Porsbjerg… - PLoS …, 2016 - journals.plos.org
Asthma is a common disease causing cough, wheezing and shortness of breath. It has been
shown that the lung microbiota in asthma patients is different from the lung microbiota in …
shown that the lung microbiota in asthma patients is different from the lung microbiota in …
Investigation of leukocyte telomere length and genetic variants in chromosome 5p15. 33 as prognostic markers in lung cancer
L Kachuri, J Helby, SE Bojesen, DC Christiani… - … Biomarkers & Prevention, 2019 - AACR
Background: Lung cancer remains the leading cause of cancer mortality with relatively few
prognostic biomarkers. We investigated associations with overall survival for telomere length (…
prognostic biomarkers. We investigated associations with overall survival for telomere length (…
[HTML][HTML] Elevated plasma YKL-40 and risk of infectious disease: a prospective study of 94665 individuals from the general population
AD Kjaergaard, J Helby, JS Johansen… - Clinical Microbiology …, 2020 - Elsevier
Objectives YKL-40 is an acute phase protein elevated in patients with infectious and inflammatory
diseases. We tested the hypothesis that baseline elevated YKL-40 is associated with …
diseases. We tested the hypothesis that baseline elevated YKL-40 is associated with …
Genetic predisposition to long telomeres is associated with increased mortality after melanoma: A study of 2101 melanoma patients from hospital clinics and the …
H Ismail, J Helby, LR Hölmich… - Pigment Cell & …, 2021 - Wiley Online Library
Whether there is an association between measured and genetically predicted telomere
length and melanoma mortality is unclear. We tested the hypothesis that measured and …
length and melanoma mortality is unclear. We tested the hypothesis that measured and …
Chronic lymphocytic leukaemia clones are detectable decades before diagnosis
FJ Vojdeman, J Helby, LB Pedersen… - British journal of …, 2022 - pubmed.ncbi.nlm.nih.gov
… 1 , Jens Helby …