[HTML][HTML] A cross-sectional, population-based study measuring comorbidity among people living with HIV in Ontario
Background As people diagnosed with HIV and receiving combination antiretroviral therapy
are now living longer, they are likely to acquire chronic conditions related to normal ageing …
are now living longer, they are likely to acquire chronic conditions related to normal ageing …
Off-label indications for antidepressants in primary care: descriptive study of prescriptions from an indication based electronic prescribing system
Objective To examine off-label indications for antidepressants in primary care and
determine the level of scientific support for off-label prescribing. Design Descriptive study of …
determine the level of scientific support for off-label prescribing. Design Descriptive study of …
[HTML][HTML] LACE+ index: extension of a validated index to predict early death or urgent readmission after hospital discharge using administrative data
C van Walraven, J Wong, AJ Forster - Open Medicine, 2012 - ncbi.nlm.nih.gov
Background Death or urgent readmission after hospital discharge is a common adverse event
that can be used to compare outcomes of care between institutions. To accurately adjust …
that can be used to compare outcomes of care between institutions. To accurately adjust …
Validation of international algorithms to identify adults with inflammatory bowel disease in health administrative data from Ontario, Canada
Objective Health administrative databases can be used to track disease incidence, outcomes,
and care quality. Case validation is necessary to ensure accurate disease ascertainment …
and care quality. Case validation is necessary to ensure accurate disease ascertainment …
Treatment indications for antidepressants prescribed in primary care in Quebec, Canada, 2006-2015
Methods| This study used data from the Medical Office of the 21st Century (MOXXI) research
platform. 3 MOXXI is an electronic medical record (EMR) and prescribing system that has …
platform. 3 MOXXI is an electronic medical record (EMR) and prescribing system that has …
[HTML][HTML] A novel non-invasive method to detect excessively high respiratory effort and dynamic transpulmonary driving pressure during mechanical ventilation
…, E Fan, C Sinderby, J Beck, L Liu, H Qiu, J Wong… - Critical Care, 2019 - Springer
Background Excessive respiratory muscle effort during mechanical ventilation may cause
patient self-inflicted lung injury and load-induced diaphragm myotrauma, but there are no non-…
patient self-inflicted lung injury and load-induced diaphragm myotrauma, but there are no non-…
Long-term efavirenz use is associated with worse neurocognitive functioning in HIV-infected patients
Neurocognitive (NC) complications continue to afflict a substantial proportion of HIV-infected
people taking effective antiretroviral therapy (ART). One contributing mechanism for this is …
people taking effective antiretroviral therapy (ART). One contributing mechanism for this is …
Breast Cancer Index Predicts Extended Endocrine Benefit to Individualize Selection of Patients with HR+ Early-stage Breast Cancer for 10 Years of Endocrine …
Purpose: Individualized selection of patients with early-stage hormone receptor–positive (HR
+ ) breast cancer for extended endocrine therapy (EET) is required to balance modest …
+ ) breast cancer for extended endocrine therapy (EET) is required to balance modest …
[HTML][HTML] Strategies for lung-and diaphragm-protective ventilation in acute hypoxemic respiratory failure: a physiological trial
J Dianti, S Fard, J Wong, TCY Chan, L Del Sorbo… - Critical Care, 2022 - Springer
Background Insufficient or excessive respiratory effort during acute hypoxemic respiratory
failure (AHRF) increases the risk of lung and diaphragm injury. We sought to establish whether …
failure (AHRF) increases the risk of lung and diaphragm injury. We sought to establish whether …
A dynamic predictive model for progression of CKD
Background Predicting the progression of chronic kidney disease (CKD) is vital for clinical
decision making and patient-provider communication. We previously developed an accurate …
decision making and patient-provider communication. We previously developed an accurate …