User profiles for Jeffrey A. Johnson

Jeffrey A. Johnson

- Verified email at ualberta.ca - Cited by 49242

Jeffrey A Johnson

- Verified email at wisc.edu - Cited by 18582

[HTML][HTML] Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana

…, E Buliva, RJ Gvetadze, S Johnson… - New England journal …, 2012 - Mass Medical Soc
Background Preexposure prophylaxis with antiretroviral agents has been shown to reduce
the transmission of human immunodeficiency virus (HIV) among men who have sex with men; …

US valuation of the EQ-5D health states: development and testing of the D1 valuation model

JW Shaw, JA Johnson, SJ Coons - Medical care, 2005 - journals.lww.com
Purpose: The EQ-5D is a brief, multiattribute, preference-based health status measure. This
article describes the development of a statistical model for generating US population-based …

Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress

AY Shih, DA Johnson, G Wong, AD Kraft… - Journal of …, 2003 - Soc Neuroscience
Astrocytes have a higher antioxidant potential in comparison to neurons. Pathways associated
with this selective advantage include the transcriptional regulation of antioxidant enzymes …

Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin

…, SR Majumdar, P Veugelers, JA Johnson - Diabetes …, 2006 - Am Diabetes Assoc
OBJECTIVE—Numerous studies have identified an increased risk of cancer in type 2 diabetes.
We explored the association between antidiabetic therapies and cancer-related mortality …

The Nrf2–ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

JA Johnson, DA Johnson, AD Kraft… - Annals of the new …, 2008 - Wiley Online Library
Transcriptional activation of protective genes is mediated by a cis‐acting element called the
antioxidant responsive element (ARE). The transcription factor Nrf2 (NF–E2‐related factor 2) …

Seroprevalence of antibodies to SARS-CoV-2 in 10 sites in the United States, March 23-May 12, 2020

…, L Mills, DS Carroll, SM Owen, JA Johnson… - JAMA internal …, 2020 - jamanetwork.com
Importance Reported cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection likely underestimate the prevalence of infection in affected communities. Large-…

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in …

AD Kraft, DA Johnson, JA Johnson - Journal of Neuroscience, 2004 - Soc Neuroscience
Binding of the transcription factor nuclear factor E2-related factor 2 (Nrf2) to the antioxidant
response element (ARE) in neural cells results in the induction of a battery of genes that can …

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

…, DA Johnson, YW Kan, JA Johnson - Proceedings of the …, 2009 - National Acad Sciences
Oxidative stress has been implicated in the etiology of Parkinson's disease (PD) and in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP) animal model of PD. It is known that …

[HTML][HTML] An important role of Nrf2-ARE pathway in the cellular defense mechanism

JM Lee, JA Johnson - BMB Reports, 2004 - koreascience.kr
The antioxidant responsive element (ARE) is a cis-acting regulatory element of genes encoding
phase II detoxification enzymes and antioxidant proteins, such as NAD (P) H: quinone …

[HTML][HTML] Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide …

…, MJ Calkins, K Chan, YW Kan, JA Johnson - Journal of Biological …, 2003 - ASBMB
The antioxidant responsive element (ARE) mediates transcriptional regulation of phase II
detoxification enzymes and antioxidant proteins such as NAD(P)H:quinone oxidoreductase (…