The pbuE adenine riboswitch undergoes metal ion-dependent folding that involves a loop-loop
interaction. Binding of 2-aminopurine to the aptamer domain strongly correlates with the …

Context Contemporary studies have shown that traditional medical school admissions
interviews have strong face validity but provide evidence for only low reliability and validity. As a …

Many bacterial mRNAs are regulated at the transcriptional or translational level by ligand-binding
elements called riboswitches. Although they both bind adenine, the adenine …

The exosome is an RNA-decay complex that constantly monitors transcription and contributes
to post-transcriptional turnover of faulty mRNAs. Yet how nuclear RNA surveillance by the …

We report on the development of surface plasmon resonance (SPR) sensors and matching
ELISAs for the detection of nucleocapsid and spike antibodies specific against the novel …

The addition of a 3’ poly(A) tail is a pre-requisite for the maturation of the majority of eukaryotic
transcripts. In most eukaryotic species, RNA poly(A) tails are bound by two important poly(…

Infantile colic is characterised by episodes of uncontrollable crying or fussing in an otherwise
healthy and well-fed infant less than three months of age. The episodes of crying in an …

… Jean-François Lemay is supported by a doctoral scholarship from the Fonds de la recherche
du Québec-Santé (FRQS). Dany Gagnon holds a Junior 1 Career Award from the FRQS. …

Termination of RNA polymerase II (RNAPII) transcription is associated with RNA 3′ end
formation. For coding genes, termination is initiated by the cleavage/polyadenylation machinery…

Long noncoding RNAs (lncRNAs), which are longer than 200 nucleotides but often unstable,
contribute a substantial and diverse portion to pervasive noncoding transcriptomes. Most …