Protein acetylation, especially histone acetylation, is the subject of both research and clinical
investigation. At least four small-molecule histone deacetylase inhibitors are currently in …

Over the course of the last two decades, athletes have received increased demands on their
performance. This has determined an increase in the risk of acute and overuse sport injuries…

We have shown that the proteasome inhibitor bortezomib (formerly known as PS-341)
triggers significant antitumor activity in multiple myeloma (MM) in both preclinical models and …

CONTEXT: Emerging evidence suggests that sedentary behavior (ie, time spent sitting) may
be negatively associated with health. The aim of this study was to systematically review the …

Comparative analysis of prostateâ•’specific antigen free survival outcomes for patients with
low, intermediate and high ris Page 1 © 2012 THE AUTHORS 2 2 BJU INTERNATIONAL © …

The skin is often viewed as a static barrier that protects the body from the outside world.
Emphasis on studying the skin's architecture and biomechanics in the context of restoring skin …

Gastric cancer displays marked molecular heterogeneity with aggressive behavior and
treatment resistance. Therefore, good in vitro models that encompass unique subtypes are …

Intron retention (IR) is widely recognized as a consequence of mis-splicing that leads to failed
excision of intronic sequences from pre-messenger RNAs. Our bioinformatic analyses of …

A functioning nanomachine in the form of a supramolecular nanovalve that opens and
closes the orifices to molecular-sized pores and releases a small number of molecules on …

G-quadruplex DNAs form four-stranded helical structures and are proposed to play key roles
in different cellular processes. Targeting G-quadruplex DNAs for cancer treatment is a very …