A majority of pregnant women take at least one medication during pregnancy, although the
safety of such drugs during pregnancy is not always known. We reviewed the safety during …

Azathioprine (AZA) and its active metabolite, 6-mercaptopurine (6-MP), are purine
analogues that interfere with the synthesis of adenine and guanine ribonucleosides. These …

We aimed to estimate the reliability of the 4‐item Perceived Stress Scale (PSS) and its
validity in predicting maternal depression and quality of life (QoL). Data regarding stress, …

In patients with psoriasis, there is an increased availability of drugs for treatment. However,
there are important questions about drug safety for mothers with psoriasis and their fetuses. …

Teratogenic exposures are those that can cause an embryo or fetus to develop abnormally.
Several factors determine whether an agent is teratogenic, including the gestational timing of …

Although clinical trials address questions regarding drug safety for most segments of the
population, pregnant women constitute one special group that is “orphaned” with respect to this …

Background Most congenital defects associated with prenatal exposures are notable for a
pattern of major and minor malformations, rather than for a single major malformation. Thus, …

Drugs that interfere with the renin‐angiotensin system, such as angiotensin‐converting enzyme
inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), are widely used to manage …

Relatively few drugs, especially those recently approved by the US Food and Drug
Administration, have published human pregnancy experience. Although all drugs contain animal …

… Polifka and Friedman … Misoprostol is a synthetic analogue of prostaglandin E, used in the
prophylaxis and treatment of peptic ulcer disease. Misoprostol is also used by women to induce …