User profiles for Jamie L. Fleet

Jamie L Fleet

Western University
Verified email at sjhc.london.on.ca
Cited by 1375

Calcium-channel blocker–clarithromycin drug interactions and acute kidney injury

S Gandhi, JL Fleet, DG Bailey, E McArthur, R Wald… - Jama, 2013 - jamanetwork.com
Importance Calcium-channel blockers are metabolized by the cytochrome P450 3A4 (CYP3A4;
EC 1.14.13.97) enzyme. Blood concentrations of these drugs may rise to harmful levels …

[HTML][HTML] Detecting chronic kidney disease in population-based administrative databases using an algorithm of hospital encounter and physician claim codes

JL Fleet, SN Dixon, SZ Shariff, RR Quinn, DM Nash… - BMC nephrology, 2013 - Springer
Background Large, population-based administrative healthcare databases can be used to
identify patients with chronic kidney disease (CKD) when serum creatinine laboratory results …

Validity of the International Classification of Diseases, Tenth Revision code for acute kidney injury in elderly patients at presentation to the emergency department and …

…, SZ Shariff, S Gandhi, R Wald, E Clark, JL Fleet… - BMJ open, 2012 - bmjopen.bmj.com
Objective To evaluate the validity of the International Classification of Diseases, Tenth
Revision (ICD-10) code N17x for acute kidney injury (AKI) in elderly patients in two settings: at …

β-Blocker dialyzability and mortality in older patients receiving hemodialysis

MA Weir, SN Dixon, JL Fleet, MA Roberts… - Journal of the …, 2015 - journals.lww.com
Some β-blockers are efficiently removed from the circulation by hemodialysis (“high
dialyzability”) whereas others are not (“low dialyzability”). This characteristic may influence the …

Validity of the International Classification of Diseases 10th revision code for hyperkalaemia in elderly patients at presentation to an emergency department and at …

JL Fleet, SZ Shariff, S Gandhi, MA Weir, AK Jain… - BMJ open, 2012 - bmjopen.bmj.com
Objectives Evaluate the validity of the International Classification of Diseases, 10th revision (ICD-10)
code for hyperkalaemia (E87.5) in two settings: at presentation to an emergency …

Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4

DQ Li, R Kim, E McArthur, JL Fleet, DG Bailey… - Cmaj, 2015 - Can Med Assoc
Background: The cytochrome P450 3A4 (CYP3A4) inhibitor clarithromycin may also inhibit
liver-specific organic anion–transporting polypeptides (OATP1B1 and OATP1B3). We studied …

[HTML][HTML] Gabapentin dose and the 30-day risk of altered mental status in older adults: A retrospective population-based study

JL Fleet, SN Dixon, PJ Kuwornu, VK Dev… - PloS one, 2018 - journals.plos.org
Gabapentin is an effective treatment for chronic neuropathic pain but may cause dizziness,
drowsiness, and confusion in some older adults. The goal of this study was to assess the …

Hyponatremia and sodium picosulfate bowel preparations in older adults

MA Weir, JL Fleet, C Vinden, SZ Shariff… - Official journal of the …, 2014 - journals.lww.com
OBJECTIVES: Bowel preparations are commonly prescribed drugs. Case reports and our
clinical experience suggest that sodium picosulfate bowel preparations can precipitate severe …

Higher-dose gabapentinoids and the risk of adverse events in older adults with CKD: a population-based cohort study

…, F Ahmadi, JM Sontrop, A Cowan, JL Fleet… - American Journal of …, 2022 - Elsevier
Rationale & Objective Gabapentinoids are opioid substitutes whose elimination by the
kidneys is reduced as kidney function declines. To inform their safe prescribing in older adults …

The hypoglycemic risk of glyburide (glibenclamide) compared with modified-release gliclazide

KK Clemens, E McArthur, SN Dixon, JL Fleet… - Canadian journal of …, 2015 - Elsevier
Objectives The risk for hypoglycemia when taking glyburide compared with modified-release
gliclazide remains to be established in older adults in routine care. We investigated the risk …