User profiles for Jamie L. Fleet
Jamie L FleetWestern University Verified email at sjhc.london.on.ca Cited by 1375 |
Calcium-channel blocker–clarithromycin drug interactions and acute kidney injury
S Gandhi, JL Fleet, DG Bailey, E McArthur, R Wald… - Jama, 2013 - jamanetwork.com
Importance Calcium-channel blockers are metabolized by the cytochrome P450 3A4 (CYP3A4;
EC 1.14.13.97) enzyme. Blood concentrations of these drugs may rise to harmful levels …
EC 1.14.13.97) enzyme. Blood concentrations of these drugs may rise to harmful levels …
[HTML][HTML] Detecting chronic kidney disease in population-based administrative databases using an algorithm of hospital encounter and physician claim codes
Background Large, population-based administrative healthcare databases can be used to
identify patients with chronic kidney disease (CKD) when serum creatinine laboratory results …
identify patients with chronic kidney disease (CKD) when serum creatinine laboratory results …
Validity of the International Classification of Diseases, Tenth Revision code for acute kidney injury in elderly patients at presentation to the emergency department and …
Objective To evaluate the validity of the International Classification of Diseases, Tenth
Revision (ICD-10) code N17x for acute kidney injury (AKI) in elderly patients in two settings: at …
Revision (ICD-10) code N17x for acute kidney injury (AKI) in elderly patients in two settings: at …
β-Blocker dialyzability and mortality in older patients receiving hemodialysis
Some β-blockers are efficiently removed from the circulation by hemodialysis (“high
dialyzability”) whereas others are not (“low dialyzability”). This characteristic may influence the …
dialyzability”) whereas others are not (“low dialyzability”). This characteristic may influence the …
Validity of the International Classification of Diseases 10th revision code for hyperkalaemia in elderly patients at presentation to an emergency department and at …
JL Fleet, SZ Shariff, S Gandhi, MA Weir, AK Jain… - BMJ open, 2012 - bmjopen.bmj.com
Objectives Evaluate the validity of the International Classification of Diseases, 10th revision (ICD-10)
code for hyperkalaemia (E87.5) in two settings: at presentation to an emergency …
code for hyperkalaemia (E87.5) in two settings: at presentation to an emergency …
Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4
Background: The cytochrome P450 3A4 (CYP3A4) inhibitor clarithromycin may also inhibit
liver-specific organic anion–transporting polypeptides (OATP1B1 and OATP1B3). We studied …
liver-specific organic anion–transporting polypeptides (OATP1B1 and OATP1B3). We studied …
[HTML][HTML] Gabapentin dose and the 30-day risk of altered mental status in older adults: A retrospective population-based study
Gabapentin is an effective treatment for chronic neuropathic pain but may cause dizziness,
drowsiness, and confusion in some older adults. The goal of this study was to assess the …
drowsiness, and confusion in some older adults. The goal of this study was to assess the …
Hyponatremia and sodium picosulfate bowel preparations in older adults
MA Weir, JL Fleet, C Vinden, SZ Shariff… - Official journal of the …, 2014 - journals.lww.com
OBJECTIVES: Bowel preparations are commonly prescribed drugs. Case reports and our
clinical experience suggest that sodium picosulfate bowel preparations can precipitate severe …
clinical experience suggest that sodium picosulfate bowel preparations can precipitate severe …
Higher-dose gabapentinoids and the risk of adverse events in older adults with CKD: a population-based cohort study
Rationale & Objective Gabapentinoids are opioid substitutes whose elimination by the
kidneys is reduced as kidney function declines. To inform their safe prescribing in older adults …
kidneys is reduced as kidney function declines. To inform their safe prescribing in older adults …
The hypoglycemic risk of glyburide (glibenclamide) compared with modified-release gliclazide
Objectives The risk for hypoglycemia when taking glyburide compared with modified-release
gliclazide remains to be established in older adults in routine care. We investigated the risk …
gliclazide remains to be established in older adults in routine care. We investigated the risk …