User profiles for Jacques Schrenzel

Jacques Schrenzel

Professeur de médecine, Université de Genève
Verified email at hcuge.ch
Cited by 28702

De novo bacterial genome sequencing: millions of very short reads assembled on a desktop computer

…, P François, L Farinelli, M Østerås, J Schrenzel - Genome …, 2008 - genome.cshlp.org
Novel high-throughput DNA sequencing technologies allow researchers to characterize a
bacterial genome during a single experiment and at a moderate cost. However, the increase …

Comparison of two matrix-assisted laser desorption ionization-time of flight mass spectrometry methods with conventional phenotypic identification for routine …

…, M Girard, P Francois, J Schrenzel - Journal of clinical …, 2010 - Am Soc Microbiol
Bacterial identification relies primarily on culture-based methodologies requiring 24 h for
isolation and an additional 24 to 48 h for species identification. Matrix-assisted laser desorption …

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

…, F Backhed, NM Delzenne, J Schrenzel… - The ISME …, 2014 - academic.oup.com
The gut microbiota is involved in metabolic and immune disorders associated with obesity
and type 2 diabetes. We previously demonstrated that prebiotic treatment may significantly …

Robustness of a loop-mediated isothermal amplification reaction for diagnostic applications

…, T Notomi, MD Perkins, J Schrenzel - FEMS Immunology & …, 2011 - academic.oup.com
We evaluated the robustness of loop-mediated isothermal amplification (LAMP) of DNA for
bacterial diagnostic applications. Salmonella enterica serovar Typhi was used as the target …

[HTML][HTML] Study of inter-and intra-individual variations in the salivary microbiota

…, K Whiteson, D Hernandez, P François, J Schrenzel - BMC genomics, 2010 - Springer
Background Oral bacterial communities contain species that promote health and others that
have been implicated in oral and/or systemic diseases. Culture-independent approaches …

[HTML][HTML] A global view of Staphylococcus aureus whole genome expression upon internalization in human epithelial cells

…, DP Lew, P Vaudaux, WL Kelley, J Schrenzel - BMC genomics, 2007 - Springer
Background Staphylococcus aureus, a leading cause of chronic or acute infections, is
traditionally considered an extracellular pathogen despite repeated reports of S. aureus …

A type III-like restriction endonuclease functions as a major barrier to horizontal gene transfer in clinical Staphylococcus aureus strains

…, K Perron, P Linder, J Schrenzel - Proceedings of the …, 2010 - National Acad Sciences
Staphylococcus aureus is an versatile pathogen that can cause life-threatening infections.
Depending on the clinical setting, up to 50% of S. aureus infections are caused by methicillin-…

Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice

…, P François, WM de Vos, NM Delzenne, J Schrenzel… - …, 2011 - Am Diabetes Assoc
OBJECTIVE To investigate deep and comprehensive analysis of gut microbial communities
and biological parameters after prebiotic administration in obese and diabetic mice. …

The CodY pleiotropic repressor controls virulence in gram-positive pathogens

…, C Wolz, P Linder, J Schrenzel - FEMS Immunology & …, 2011 - academic.oup.com
CodY is involved in the adaptive response to starvation in at least 30 different low G+C gram-positive
bacteria. After dimerization and activation by cofactor binding, CodY binds to a …

Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients

S Harbarth, C Fankhauser, J Schrenzel, J Christenson… - Jama, 2008 - jamanetwork.com
Context Experts and policy makers have repeatedly called for universal screening at
hospital admission to reduce nosocomial methicillin-resistant Staphylococcus aureus (MRSA) …