RNA G-quadruplexes and their potential regulatory roles in translation

J Song, JP Perreault, I Topisirovic, S Richard - Translation, 2016 - Taylor & Francis
DNA guanine (G)-rich 4-stranded helical nucleic acid structures called G-quadruplexes (G4),
have been extensively studied during the last decades. However, emerging evidence …

Current overview on viroid–host interactions

…, JP Perreault - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Viroids are one of the most enigmatic highly structured, circular, single‐stranded RNA
phytopathogens. Although they are not known to code for any peptide, viroids induce visible …

Efficacy and safety of finasteride therapy for benign prostatic hyperplasia: results of a 2-year randomized controlled trial (the PROSPECT study). PROscar Safety Plus …

…, RC Boake, PJ Pommerville, JP Perreault… - CMAJ: Canadian …, 1996 - ncbi.nlm.nih.gov
OBJECTIVE: To evaluate the efficacy and safety of 2 years' treatment of moderate benign
prostatic hyperplasia (BPH) with finasteride. DESIGN: Double-blind, parallel-group, placebo-…

[HTML][HTML] Hop latent viroid: A hidden threat to the cannabis industry

CR Adkar-Purushothama, T Sano, JP Perreault - Viruses, 2023 - mdpi.com
… These measures have seen the virtual elimination of HSVd from the Kirin Brewery yards in
Japan [10]. Among the different heat and chemical treatments tested for tool sanitation against …

5′-UTR G-quadruplex structures acting as translational repressors

JD Beaudoin, JP Perreault - Nucleic acids research, 2010 - academic.oup.com
Given that greater than 90% of the human genome is expressed, it is logical to assume that
post-transcriptional regulatory mechanisms must be the primary means of controlling the flow …

Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening

JD Beaudoin, JP Perreault - Nucleic acids research, 2013 - academic.oup.com
… JDB and JP.P analyzed the data and wrote the manuscript … JP.P. held the Canada Research
Chair in Genomics and … JP.P. is member of the Centre de Recherche Clinique Étienne-…

Small RNA Derived from the Virulence Modulating Region of the Potato spindle tuber viroid Silences callose synthase Genes of Tomato Plants

…, T Giguère, T Sano, P Moffett, JP Perreault - The Plant …, 2015 - academic.oup.com
The tomato (Solanum lycopersicum) callose synthase genes CalS11-like and CalS12-like
encode proteins that are essential for the formation of callose, a major component of pollen …

New scoring system to identify RNA G-quadruplex folding

JD Beaudoin, R Jodoin, JP Perreault - Nucleic acids research, 2013 - academic.oup.com
… Rouleau, JD Beaudoin and JP Perreault, unpublished data]. RNA G4 folding is decidedly
more complex than meets the eye. For instance, the same transcript could perhaps generate …

3′ UTR G-quadruplexes regulate miRNA binding

…, JPS Glouzon, A Brumwell, M Bisaillon, JP Perreault - Rna, 2017 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are small noncoding RNAs that repress the translation of their target
genes. It has previously been shown that a target's availability to miRNA can be affected by its …

Clinicians are poor raters of life‐expectancy before radical prostatectomy or definitive radiotherapy for localized prostate cancer

…, SF Shariat, M McCormack, JP Perreault… - BJU …, 2007 - Wiley Online Library
OBJECTIVE To test the accuracy of predicting life‐expectancy (LE) among 19 raters, as the
accurate prediction of LE in candidates for definitive therapy for localized prostate cancer is …