Pioneer factors as master regulators of the epigenome and cell fate

A Balsalobre, J Drouin - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Pioneer factors are transcription factors with the unique ability to initiate opening of closed
chromatin. The stability of cell identity relies on robust mechanisms that maintain the …

[HTML][HTML] Pioneer transcription factors shape the epigenetic landscape

A Mayran, J Drouin - Journal of Biological Chemistry, 2018 - ASBMB
Pioneer transcription factors have the unique and important role of unmasking chromatin
domains during development to allow the implementation of new cellular programs. Compared …

Sequence and organization of the human mitochondrial genome

…, BG Barrell, MHL de Bruijn, AR Coulson, J Drouin… - Nature, 1981 - nature.com
The complete sequence of the 16,569-base pair human mitochondrial genome is presented.
The genes for the 12S and 16S rRNAs, 22 tRNAs, cytochrome c oxidase subunits I, II and III…

Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction

…, JC Chambard, YL Sun, T Smeal, TJ Schmidt, J Drouin… - Cell, 1990 - cell.com
Giucocorticoids are potent inhibitors of coiiagenase induction by phorbol esters and
inflammatory mediators. The target for this negatlve effect is the AP1 site within the coiiagenase …

A tridimensional view of pituitary development and function

…, DJ Hodson, C Lafont, K Rizzoti, J Drouin - Trends in Endocrinology …, 2012 - cell.com
Recent advances in tridimensional (3D) tissue imaging have considerably enriched our
view of the pituitary gland and its development. Whereas traditional histology of the pituitary …

Reliability and validity of the Biodex system 3 pro isokinetic dynamometer velocity, torque and position measurements

JM Drouin, TC Valovich-mcLeod, SJ Shultz… - European journal of …, 2004 - Springer
This study quantitatively assessed the mechanical reliability and validity of position, torque
and velocity measurements of the Biodex System 3 isokinetic dynamometer. Trial-to-trial and …

A different genetic code in human mitochondria

BG Barrell, AT Bankier, J Drouin - Nature, 1979 - nature.com
Abstract Comparison of the human mitochrondrial DNA sequence of the cytochrome oxidase
subunit II gene and the sequence of the corresponding beef heart protein shows that UGA …

Low‐temperature aging of Y‐TZP ceramics

J Chevalier, B Cales, JM Drouin - Journal of the American …, 1999 - Wiley Online Library
The isothermal tetragonal‐to‐monoclinic transformation of a 3Y‐TZP ceramic is investigated
from 70 to 130C in water and in steam by X‐ray diffraction and optical interferometer …

A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons

…, G Wolterink, J Drouin… - Proceedings of the …, 1997 - National Acad Sciences
The mesencephalic dopaminergic (mesDA) system regulates behavior and movement control
and has been implicated in psychiatric and affective disorders. We have identified a bicoid-…

[HTML][HTML] A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins

…, T Lamonerie, Y Gauthier, T Brue, A Enjalbert, J Drouin - Cell, 2001 - cell.com
… At E13.5, all corticotrophs (H and J) expressed Tpit (I and J) but some cells only expressed
Tpit (indicated by arrows in [J]); this would be consistent with an earlier onset of Tpit …