User profiles for Hui Zheng
Hui ZhengShanghaiTech University Verified email at shanghaitech.edu.cn Cited by 2993 |
SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development
The oocyte epigenome plays critical roles in mammalian gametogenesis and embryogenesis.
Yet, how it is established remains elusive. Here, we report that histone-lysine N-…
Yet, how it is established remains elusive. Here, we report that histone-lysine N-…
[HTML][HTML] Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice
…, LE Goldstein, RD Moir, JT Lim, K Beyreuther, H Zheng… - Neuron, 2001 - cell.com
Inhibition of neocortical β-amyloid (Aβ) accumulation may be essential in an effective therapeutic
intervention for Alzheimer's disease (AD). Cu and Zn are enriched in Aβ deposits in AD, …
intervention for Alzheimer's disease (AD). Cu and Zn are enriched in Aβ deposits in AD, …
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance: the Da Qing IGT and Diabetes Study
…, PA Liu, XG Jiang, YY Jiang, JP Wang, H Zheng… - Diabetes …, 1997 - Am Diabetes Assoc
OBJECTIVE Individuals with impaired glucose tolerance (IGT) have a high risk of developing
NIDDM. The purpose of this study was to determine whether diet and exercise interventions …
NIDDM. The purpose of this study was to determine whether diet and exercise interventions …
[PDF][PDF] Meta-analysis of the Alzheimer's disease human brain transcriptome and functional dissection in mouse models
We present a consensus atlas of the human brain transcriptome in Alzheimer's disease (AD),
based on meta-analysis of differential gene expression in 2,114 postmortem samples. We …
based on meta-analysis of differential gene expression in 2,114 postmortem samples. We …
β-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
H Zheng, M Jiang, ME Trumbauer, DJS Sirinathsinghji… - Cell, 1995 - cell.com
In several pedigrees of early onset familial Alzheimer’s disease (FAD), point mutations in the
(I-amyloid precursor protein (APP) gene are genetically linked to the disease. This finding …
(I-amyloid precursor protein (APP) gene are genetically linked to the disease. This finding …
Translating the A1C assay into estimated average glucose values
DM Nathan, J Kuenen, R Borg, H Zheng… - Diabetes …, 2008 - Am Diabetes Assoc
OBJECTIVE—The A1C assay, expressed as the percent of hemoglobin that is glycated,
measures chronic glycemia and is widely used to judge the adequacy of diabetes treatment and …
measures chronic glycemia and is widely used to judge the adequacy of diabetes treatment and …
Epidemiological serosurvey of hepatitis B in China—declining HBV prevalence due to hepatitis B vaccination
…, Y Zhang, J Liu, X Gong, Y Chen, F Wang, H Zheng… - vaccine, 2009 - Elsevier
OBJECTIVE: To determine the prevalence of hepatitis B surface antigen (HBsAg), hepatitis
B surface antibody (anti-HBs), and hepatitis B core anti-body (anti-HBc) in a representative …
B surface antibody (anti-HBs), and hepatitis B core anti-body (anti-HBc) in a representative …
Immunoregulation in diabetic wound repair with a photoenhanced glycyrrhizic acid hydrogel scaffold
Y Qian, Y Zheng, J Jin, X Wu, K Xu, M Dai… - Advanced …, 2022 - Wiley Online Library
M1 macrophage accumulation and excessive inflammation are commonly encountered
issues in diabetic wounds and can fail in the healing process. Hence, hydrogel dressings with …
issues in diabetic wounds and can fail in the healing process. Hence, hydrogel dressings with …
[HTML][HTML] MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
In response to viral infection, RIG-I-like RNA helicases bind to viral RNA and activate the
mitochondrial protein MAVS, which in turn activates the transcription factors IRF3 and NF-κB to …
mitochondrial protein MAVS, which in turn activates the transcription factors IRF3 and NF-κB to …
[HTML][HTML] Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels
…, K Stephan, S Bova, H Chen, H Zheng… - Cell, 2000 - cell.com
Voltage-gated L-type Ca 2+ channels (LTCCs) containing a pore-forming α1D subunit (D-LTCCs)
are expressed in neurons and neuroendocrine cells. Their relative contribution to total …
are expressed in neurons and neuroendocrine cells. Their relative contribution to total …