[HTML][HTML] Part 1 results of a dose-finding study of belantamab mafodotin in combination with pomalidomide and dexamethasone for the treatment of relapsed/refractory …

…, HJ Sutherland, ML Louzada, CP Venner, HS Mian… - Blood, 2021 - Elsevier
Background: Belantamab mafodotin (belamaf) is a first-in-class antibody-drug conjugate (ADC)
targeting B-cell maturation antigen (BCMA) that has shown clinically meaningful activity …

Development of a medicare health outcomes survey deficit-accumulation frailty index and its application to older patients with newly diagnosed multiple myeloma

HS Mian, TM Wildes, MA Fiala - JCO clinical cancer informatics, 2018 - ascopubs.org
Purpose To develop a frailty index using the Rockwood Accumulation of Deficits approach
for the Medicare Health Outcomes Survey (MHOS) and apply it in a subset of older patients …

Crystal structure of the passenger domain of the Escherichia coli autotransporter EspP

S Khan, HS Mian, LE Sandercock… - Journal of molecular …, 2011 - Elsevier
Autotransporters represent a large superfamily of known and putative virulence factors
produced by Gram-negative bacteria. They consist of an N-terminal “passenger domain” …

Geriatric assessment and frailty scores predict mortality in myeloma: systematic review and meta-analysis

…, HS Mian, C Stoll, LE Simon, S Sekhon… - … Myeloma and Leukemia, 2019 - Elsevier
The incidence of multiple myeloma is increasing as the proportion of older adults is growing
rapidly. A critical evaluation of the evidence available is needed to guide the management …

Burden of treatment among older adults with newly diagnosed multiple myeloma

HS Mian, MA Fiala, TM Wildes - Clinical Lymphoma Myeloma and …, 2021 - Elsevier
Background Multiple myeloma is an incurable hematologic malignancy with significant recent
treatment advances; however, the magnitude of treatment burden among patients in the …

Belantamab mafodotin in combination with pomalidomide and dexamethasone demonstrates durable responses in triple class exposed/refractory multiple myeloma

…, ML Louzada, MP Chu, DJ White, HS Mian… - Blood, 2022 - ashpublications.org
Background: Belantamab mafodotin (belamaf) is a first-in-class antibody-drug conjugate (ADC)
targeting B-cell maturation antigen (BCMA). Belamaf has shown clinically meaningful …

Disparities in treatment patterns and outcomes among younger and older adults with newly diagnosed multiple myeloma: a population-based study

HS Mian, H Seow, TM Wildes, CT Kouroukis… - Journal of geriatric …, 2021 - Elsevier
Introduction Multiple myeloma, a cancer of older adults, has seen significant improvement in
therapeutic options over the past two decades. Uncovering disparities in treatment patterns …

Simplified frailty assessment tools: are we really capturing frailty or something else?

…, SJ Grant, HS Mian, S Tuchman, S Zweegman… - Leukemia, 2020 - nature.com
In their recent paper “A simplified frailty scale predicts outcomes in transplant-ineligible patients
with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial”[1], Facon et …

Transplant-ineligible newly diagnosed multiple myeloma: Current and future approaches to clinical care: A Young International Society of Geriatric Oncology Review …

SJ Grant, HS Mian, S Giri, M Boutin, L Dottorini… - Journal of geriatric …, 2021 - Elsevier
Multiple myeloma is the second most common hematological malignancy in the USA and
Europe. Despite improvements in the 5-year and overall survival rates over the past decade, …

External validation of the FIRST trial's simplified frailty score in a population-based cohort

HS Mian, S Giri, TM Wildes, AK Balitsky, A McCurdy… - Leukemia, 2021 - nature.com
Multiple myeloma is a disease of older adults, with a median age of 70 at diagnosis. Better
risk stratification strategies are required to identify older, fit adults who benefit from more …